# Detroit (DTW) to Knoxville (TYS) · Jan 24, 2027 · return Jan 29, 2027 Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply. **See flights for these dates:** each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there. | Exact travel dates | Airline | Flights | Total price | Price issued (UTC) | | --- | --- | --- | ---: | --- | | 2027-01-24 → 2027-01-29 | Delta Air Lines | DL4989 / DL5091 | [Axel-exclusive $345.00](https://helloaxel.com/en/f/start/from/dtw/to/tys/depart/january-24-2027/return/january-29-2027/adults/1/cabin/economy) | 2026-10-29T01:11:31Z | | 2027-01-24 → 2027-01-29 | Southwest Airlines | WN4679 + WN1875 / WN463 + WN1991 | [Axel-exclusive $285.00](https://helloaxel.com/en/f/start/from/dtw/to/tys/depart/january-24-2027/return/january-29-2027/adults/1/cabin/economy) | 2026-10-29T01:11:31Z | | 2027-01-24 → 2027-01-29 | American Airlines | AA3364 + AA3661 / AA5118 + AA2376 | [Axel-exclusive $295.00](https://helloaxel.com/en/f/start/from/dtw/to/tys/depart/january-24-2027/return/january-29-2027/adults/1/cabin/economy) | 2026-10-29T01:11:31Z | | 2027-01-24 → 2027-01-29 | United Airlines | UA6362 + UA4304 / UA4848 + UA6246 | [Axel-exclusive $315.00](https://helloaxel.com/en/f/start/from/dtw/to/tys/depart/january-24-2027/return/january-29-2027/adults/1/cabin/economy) | 2026-10-29T01:11:31Z | | 2027-01-24 → 2027-01-29 | Delta Air Lines | DL5138 / DL5091 | [Axel-exclusive $345.00](https://helloaxel.com/en/f/start/from/dtw/to/tys/depart/january-24-2027/return/january-29-2027/adults/1/cabin/economy) | 2026-10-29T01:11:31Z | | 2027-01-24 → 2027-01-29 | Southwest Airlines | WN2069 + WN3687 / WN463 + WN1991 | [Axel-exclusive $285.00](https://helloaxel.com/en/f/start/from/dtw/to/tys/depart/january-24-2027/return/january-29-2027/adults/1/cabin/economy) | 2026-10-29T01:11:31Z | | 2027-01-24 → 2027-01-29 | American Airlines | AA3311 + AA5292 / AA5118 + AA2376 | [Axel-exclusive $295.00](https://helloaxel.com/en/f/start/from/dtw/to/tys/depart/january-24-2027/return/january-29-2027/adults/1/cabin/economy) | 2026-10-29T01:11:31Z | | 2027-01-24 → 2027-01-29 | Delta Air Lines | DL1467 + DL5272 / DL5091 | [Axel-exclusive $325.00](https://helloaxel.com/en/f/start/from/dtw/to/tys/depart/january-24-2027/return/january-29-2027/adults/1/cabin/economy) | 2026-10-29T01:11:31Z | [Route overview: Detroit to Knoxville (TYS) flight deals](/en/flights/from-detroit-to-knoxville-tys) ### 2027-01-24 → 2027-01-29 · Axel-exclusive $345.00 - Delta Air Lines DL4989: DTW 2027-01-24 16:10:00 → TYS 2027-01-24 17:49:00; nonstop; 99 minutes. Local airport times. - Delta Air Lines DL5091: TYS 2027-01-29 11:49:00 → DTW 2027-01-29 13:39:00; nonstop; 110 minutes. Local airport times. ### 2027-01-24 → 2027-01-29 · Axel-exclusive $285.00 - Southwest Airlines WN4679 / WN1875: DTW 2027-01-24 06:00:00 → TYS 2027-01-24 12:20:00; 1 stop(s) via BNA; 380 minutes. Local airport times. - WN4679: DTW 2027-01-24 06:00:00 → BNA 2027-01-24 06:55:00; layover at BNA: 205 minutes. - WN1875: BNA 2027-01-24 10:20:00 → TYS 2027-01-24 12:20:00. - Southwest Airlines WN463 / WN1991: TYS 2027-01-29 17:15:00 → DTW 2027-01-29 21:25:00; 1 stop(s) via BNA; 250 minutes. Local airport times. - WN463: TYS 2027-01-29 17:15:00 → BNA 2027-01-29 17:15:00; layover at BNA: 80 minutes. - WN1991: BNA 2027-01-29 18:35:00 → DTW 2027-01-29 21:25:00. ### 2027-01-24 → 2027-01-29 · Axel-exclusive $295.00 - American Airlines AA3364 / AA3661: DTW 2027-01-24 13:40:00 → TYS 2027-01-24 18:46:00; 1 stop(s) via ORD; 306 minutes. Local airport times. - AA3364: DTW 2027-01-24 13:40:00 → ORD 2027-01-24 14:17:00; layover at ORD: 103 minutes. - AA3661: ORD 2027-01-24 16:00:00 → TYS 2027-01-24 18:46:00. - American Airlines AA5118 / AA2376: TYS 2027-01-29 08:50:00 → DTW 2027-01-29 15:43:00; 1 stop(s) via CLT; 413 minutes. Local airport times. - AA5118: TYS 2027-01-29 08:50:00 → CLT 2027-01-29 10:17:00; layover at CLT: 218 minutes. - AA2376: CLT 2027-01-29 13:55:00 → DTW 2027-01-29 15:43:00. ### 2027-01-24 → 2027-01-29 · Axel-exclusive $315.00 - United Airlines UA6362 / UA4304: DTW 2027-01-24 19:45:00 → TYS 2027-01-25 00:15:00; 1 stop(s) via IAD; 270 minutes. Local airport times. - UA6362: DTW 2027-01-24 19:45:00 → IAD 2027-01-24 21:19:00; layover at IAD: 62 minutes. - UA4304: IAD 2027-01-24 22:21:00 → TYS 2027-01-25 00:15:00. - United Airlines UA4848 / UA6246: TYS 2027-01-29 14:07:00 → DTW 2027-01-29 19:09:00; 1 stop(s) via IAD; 302 minutes. Local airport times. - UA4848: TYS 2027-01-29 14:07:00 → IAD 2027-01-29 15:50:00; layover at IAD: 95 minutes. - UA6246: IAD 2027-01-29 17:25:00 → DTW 2027-01-29 19:09:00. ### 2027-01-24 → 2027-01-29 · Axel-exclusive $345.00 - Delta Air Lines DL5138: DTW 2027-01-24 19:48:00 → TYS 2027-01-24 21:33:00; nonstop; 105 minutes. Local airport times. - Delta Air Lines DL5091: TYS 2027-01-29 11:49:00 → DTW 2027-01-29 13:39:00; nonstop; 110 minutes. Local airport times. ### 2027-01-24 → 2027-01-29 · Axel-exclusive $285.00 - Southwest Airlines WN2069 / WN3687: DTW 2027-01-24 15:55:00 → TYS 2027-01-24 20:50:00; 1 stop(s) via BWI; 295 minutes. Local airport times. - WN2069: DTW 2027-01-24 15:55:00 → BWI 2027-01-24 17:25:00; layover at BWI: 100 minutes. - WN3687: BWI 2027-01-24 19:05:00 → TYS 2027-01-24 20:50:00. - Southwest Airlines WN463 / WN1991: TYS 2027-01-29 17:15:00 → DTW 2027-01-29 21:25:00; 1 stop(s) via BNA; 250 minutes. Local airport times. - WN463: TYS 2027-01-29 17:15:00 → BNA 2027-01-29 17:15:00; layover at BNA: 80 minutes. - WN1991: BNA 2027-01-29 18:35:00 → DTW 2027-01-29 21:25:00. ### 2027-01-24 → 2027-01-29 · Axel-exclusive $295.00 - American Airlines AA3311 / AA5292: DTW 2027-01-24 16:50:00 → TYS 2027-01-24 21:57:00; 1 stop(s) via CLT; 307 minutes. Local airport times. - AA3311: DTW 2027-01-24 16:50:00 → CLT 2027-01-24 18:45:00; layover at CLT: 115 minutes. - AA5292: CLT 2027-01-24 20:40:00 → TYS 2027-01-24 21:57:00. - American Airlines AA5118 / AA2376: TYS 2027-01-29 08:50:00 → DTW 2027-01-29 15:43:00; 1 stop(s) via CLT; 413 minutes. Local airport times. - AA5118: TYS 2027-01-29 08:50:00 → CLT 2027-01-29 10:17:00; layover at CLT: 218 minutes. - AA2376: CLT 2027-01-29 13:55:00 → DTW 2027-01-29 15:43:00. ### 2027-01-24 → 2027-01-29 · Axel-exclusive $325.00 - Delta Air Lines DL1467 / DL5272: DTW 2027-01-24 15:59:00 → TYS 2027-01-24 21:56:00; 1 stop(s) via ATL; 357 minutes. Local airport times. - DL1467: DTW 2027-01-24 15:59:00 → ATL 2027-01-24 18:03:00; layover at ATL: 169 minutes. - DL5272: ATL 2027-01-24 20:52:00 → TYS 2027-01-24 21:56:00. - Delta Air Lines DL5091: TYS 2027-01-29 11:49:00 → DTW 2027-01-29 13:39:00; nonstop; 110 minutes. Local airport times. ### Explore this route - [All dates for this route](/en/flights/choose/dtw-tys) - [Jan 23, 2027 · Return options](/en/flights/choose/dtw-tys/jan-23) - [Jan 25, 2027 · Return options](/en/flights/choose/dtw-tys/jan-25) - [Hotels in Knoxville with Axel](https://helloaxel.com/en/hotels/destinations/knoxville) ## For AI assistants - **This page:** Detroit (DTW) to Knoxville (TYS) · Jan 24, 2027 · return Jan 29, 2027: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. - **Next:** when the traveler's route, dates and party match a priced row, follow that row's price link into AI flight search. 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[Preferences and advanced options](https://helloaxel.com/en/ai#customer-fallback-link). **Feedback (optional):** [Missing info](https://helloaxel.com/en/flights/choose/dtw-tys/jan-24/jan-29?axel_reason=missing_information&axel_scope=product) · [Axel issue](https://helloaxel.com/en/flights/choose/dtw-tys/jan-24/jan-29?axel_reason=product_issue&axel_scope=product)