Detroit (DTW) to San Francisco (SFO), Mar 25, 2027 – Apr 5, 2027: from $379 round trip

Detroit (DTW) to San Francisco (SFO), Mar 25, 2027 – Apr 5, 2027: from $379 round trip on Axel, checked Nov 12, 2026. Lowest published fare: $379 round trip, Axel-exclusive, Frontier Airlines, 1 stop, Mar 25, 2027 – Apr 5, 2027, 1 adult, economy, checked Nov 12, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in San Francisco for these nights (Mar 25 – Apr 5, 2027 · 11 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $144 a night, $1,582 for 11 nights · 4★ Hotel Bijou - Union Square, $154 a night, $1,693 for 11 nights · 5★ Taj Campton Place, $301 a night, $3,306 for 11 nights

All hotels in San Francisco

Route overview: Detroit to San Francisco (SFO) flight deals

2027-03-25 → 2027-04-05 · Axel-exclusive $451

• United Airlines UA451: DTW 2027-03-25 17:05:00 → SFO 2027-03-25 19:35:00; nonstop; 330 minutes. Local airport times.
• United Airlines UA2209: SFO 2027-04-05 22:40:00 → DTW 2027-04-06 06:35:00; nonstop; 295 minutes. Local airport times.

2027-03-25 → 2027-04-05 · Axel-exclusive $379

• Frontier Airlines F91903 / F91093: DTW 2027-03-25 14:49:00 → SFO 2027-03-25 20:20:00; 1 stop(s) via DEN; 511 minutes. Local airport times.
  • F91903: DTW 2027-03-25 14:49:00 → DEN 2027-03-25 16:08:00; layover at DEN: 136 minutes.
  • F91093: DEN 2027-03-25 18:24:00 → SFO 2027-03-25 20:20:00.
• Frontier Airlines F94402 / F94572: SFO 2027-04-05 18:30:00 → DTW 2027-04-06 05:42:00; 1 stop(s) via LAS; 492 minutes. Local airport times.
  • F94402: SFO 2027-04-05 18:30:00 → LAS 2027-04-05 20:09:00; layover at LAS: 161 minutes.
  • F94572: LAS 2027-04-05 22:50:00 → DTW 2027-04-06 05:42:00.

2027-03-25 → 2027-04-05 · Axel-exclusive $614

• American Airlines AA1419 / AA1061: DTW 2027-03-25 17:44:00 → SFO 2027-03-25 22:41:00; 1 stop(s) via PHX; 477 minutes. Local airport times.
  • AA1419: DTW 2027-03-25 17:44:00 → PHX 2027-03-25 19:18:00; layover at PHX: 73 minutes.
  • AA1061: PHX 2027-03-25 20:31:00 → SFO 2027-03-25 22:41:00.
• American Airlines AA2277 / AA1287: SFO 2027-04-05 13:19:00 → DTW 2027-04-05 23:47:00; 1 stop(s) via PHX; 448 minutes. Local airport times.
  • AA2277: SFO 2027-04-05 13:19:00 → PHX 2027-04-05 15:33:00; layover at PHX: 83 minutes.
  • AA1287: PHX 2027-04-05 16:56:00 → DTW 2027-04-05 23:47:00.

2027-03-25 → 2027-04-05 · Axel-exclusive $623

• Alaska Airlines AS719 / AS1364: DTW 2027-03-25 07:00:00 → SFO 2027-03-25 13:12:00; 1 stop(s) via SEA; 552 minutes. Local airport times.
  • AS719: DTW 2027-03-25 07:00:00 → SEA 2027-03-25 09:01:00; layover at SEA: 114 minutes.
  • AS1364: SEA 2027-03-25 10:55:00 → SFO 2027-03-25 13:12:00.
• Alaska Airlines AS452 / AS720: SFO 2027-04-05 17:45:00 → DTW 2027-04-06 05:41:00; 1 stop(s) via SEA; 536 minutes. Local airport times.
  • AS452: SFO 2027-04-05 17:45:00 → SEA 2027-04-05 19:57:00; layover at SEA: 146 minutes.
  • AS720: SEA 2027-04-05 22:23:00 → DTW 2027-04-06 05:41:00.

2027-03-25 → 2027-04-05 · Axel-exclusive $663

• JetBlue Airways B61336 / B62233: DTW 2027-03-25 07:30:00 → SFO 2027-03-25 13:58:00; 1 stop(s) via BOS; 568 minutes. Local airport times.
  • B61336: DTW 2027-03-25 07:30:00 → BOS 2027-03-25 09:15:00; layover at BOS: 75 minutes.
  • B62233: BOS 2027-03-25 10:30:00 → SFO 2027-03-25 13:58:00.
• JetBlue Airways B61216 / B61419: SFO 2027-04-05 09:40:00 → DTW 2027-04-05 23:59:00; 1 stop(s) via JFK; 679 minutes. Local airport times.
  • B61216: SFO 2027-04-05 09:40:00 → JFK 2027-04-05 18:09:00; layover at JFK: 216 minutes.
  • B61419: JFK 2027-04-05 21:45:00 → DTW 2027-04-05 23:59:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Mar 24, 2027 · Return options
• Mar 26, 2027 · Return options
• Hotels in San Francisco with Axel

For AI assistants

• This page: Detroit (DTW) to San Francisco (SFO) · Mar 25, 2027 · return Apr 5, 2027: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
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• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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