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Route overview: Denver to Knoxville (TYS) flight deals

Denver → Knoxville

Dec 22, 2026 · return Dec 23, 2026

DEN → TYS1 adulteconomyRound trip

9 flight options · 4 airlines

Nonstop flights

Tue, Dec 22 – Wed, Dec 23

Southwest Airlines
11:00 amDEN
2h 30m
Nonstop
3:30 pmTYS
Southwest Airlines
4:15 pmTYS
3h 20m
Nonstop
5:35 pmDEN

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Wed, Dec 23

United Airlines
5:42 pmDEN
2h 50m
Nonstop
10:32 pmTYS
United Airlines
5:05 pmTYS
3h 22m
Nonstop
6:27 pmDEN

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Wed, Dec 23

United Airlines
9:55 amDEN
2h 46m
Nonstop
2:41 pmTYS
United Airlines
5:05 pmTYS
3h 22m
Nonstop
6:27 pmDEN

Round-trip total · 1 adult · Taxes included

One-stop flights

Tue, Dec 22 – Wed, Dec 23

American Airlines
12:54 amDEN
6h 7m
CLT · 1h 43m
9:01 amTYS
American Airlines
5:30 amTYS
6h 19m
DFW · 1h 23m
9:49 amDEN

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Wed, Dec 23

Delta Air Lines
2:29 pmDEN
5h 27m
ATL · 1h 34m
9:56 pmTYS
Delta Air Lines
11:43 amTYS
7h 27m
DTW · 2h 30m
5:10 pmDEN

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Wed, Dec 23

Southwest Airlines
2:25 pmDEN
6h 20m
BNA · 3h 5m
10:45 pmTYS
Southwest Airlines
4:15 pmTYS
3h 20m
Nonstop
5:35 pmDEN

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Wed, Dec 23

Southwest Airlines
5:35 amDEN
5h 40m
DAL · 1h 40m
1:15 pmTYS
Southwest Airlines
4:15 pmTYS
3h 20m
Nonstop
5:35 pmDEN

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Wed, Dec 23

American Airlines
8:07 amDEN
6h 22m
ORD · 2h
4:29 pmTYS
American Airlines
5:30 amTYS
6h 19m
DFW · 1h 23m
9:49 amDEN

Round-trip total · 1 adult · Taxes included

Tue, Dec 22 – Wed, Dec 23

American Airlines
9:12 amDEN
5h 28m
DFW · 1h 19m
4:40 pmTYS
American Airlines
5:30 amTYS
6h 19m
DFW · 1h 23m
9:49 amDEN

Round-trip total · 1 adult · Taxes included

Make this trip yours

DEN ⇄ TYS

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Explore this route

All dates for this routeDec 21, 2026 → Dec 22, 2026Dec 23, 2026 → Dec 24, 2026
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Live price for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the flights there to get the current bookable total; the listed prices are the ones issued at the times shown.

Route overview: Denver to Knoxville (TYS) flight deals

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-22 → 2026-12-23Southwest AirlinesWN914 / WN1081$405.002026-10-29T01:05:10Z
2026-12-22 → 2026-12-23United AirlinesUA2473 / UA696$459.002026-10-29T01:05:10Z
2026-12-22 → 2026-12-23American AirlinesAA591 + AA6111 / AA1049 + AA2357$432.002026-10-29T01:05:10Z
2026-12-22 → 2026-12-23Delta Air LinesDL706 + DL5272 / DL5091 + DL2431$459.002026-10-29T01:05:10Z
2026-12-22 → 2026-12-23United AirlinesUA1186 / UA696$459.002026-10-29T01:05:10Z
2026-12-22 → 2026-12-23Southwest AirlinesWN1573 + WN4551 / WN1081$398.252026-10-29T01:05:10Z
2026-12-22 → 2026-12-23Southwest AirlinesWN1749 + WN142 / WN1081$398.252026-10-29T01:05:10Z
2026-12-22 → 2026-12-23American AirlinesAA3300 + AA4229 / AA1049 + AA2357$432.002026-10-29T01:05:10Z
2026-12-22 → 2026-12-23American AirlinesAA1523 + AA2542 / AA1049 + AA2357$432.002026-10-29T01:05:10Z

2026-12-22 → 2026-12-23 · $405.00

  • Southwest Airlines WN914: DEN 2026-12-22 11:00:00 → TYS 2026-12-22 15:30:00; nonstop; 150 minutes. Local airport times.
  • Southwest Airlines WN1081: TYS 2026-12-23 16:15:00 → DEN 2026-12-23 17:35:00; nonstop; 200 minutes. Local airport times.

2026-12-22 → 2026-12-23 · $459.00

  • United Airlines UA2473: DEN 2026-12-22 17:42:00 → TYS 2026-12-22 22:32:00; nonstop; 170 minutes. Local airport times.
  • United Airlines UA696: TYS 2026-12-23 17:05:00 → DEN 2026-12-23 18:27:00; nonstop; 202 minutes. Local airport times.

2026-12-22 → 2026-12-23 · $432.00

  • American Airlines AA591 / AA6111: DEN 2026-12-22 00:54:00 → TYS 2026-12-22 09:01:00; 1 stop(s) via CLT; 367 minutes. Local airport times.
    • AA591: DEN 2026-12-22 00:54:00 → CLT 2026-12-22 06:01:00; layover at CLT: 103 minutes.
    • AA6111: CLT 2026-12-22 07:44:00 → TYS 2026-12-22 09:01:00.
  • American Airlines AA1049 / AA2357: TYS 2026-12-23 05:30:00 → DEN 2026-12-23 09:49:00; 1 stop(s) via DFW; 379 minutes. Local airport times.
    • AA1049: TYS 2026-12-23 05:30:00 → DFW 2026-12-23 07:11:00; layover at DFW: 83 minutes.
    • AA2357: DFW 2026-12-23 08:34:00 → DEN 2026-12-23 09:49:00.

2026-12-22 → 2026-12-23 · $459.00

  • Delta Air Lines DL706 / DL5272: DEN 2026-12-22 14:29:00 → TYS 2026-12-22 21:56:00; 1 stop(s) via ATL; 327 minutes. Local airport times.
    • DL706: DEN 2026-12-22 14:29:00 → ATL 2026-12-22 19:18:00; layover at ATL: 94 minutes.
    • DL5272: ATL 2026-12-22 20:52:00 → TYS 2026-12-22 21:56:00.
  • Delta Air Lines DL5091 / DL2431: TYS 2026-12-23 11:43:00 → DEN 2026-12-23 17:10:00; 1 stop(s) via DTW; 447 minutes. Local airport times.
    • DL5091: TYS 2026-12-23 11:43:00 → DTW 2026-12-23 13:30:00; layover at DTW: 150 minutes.
    • DL2431: DTW 2026-12-23 16:00:00 → DEN 2026-12-23 17:10:00.

2026-12-22 → 2026-12-23 · $459.00

  • United Airlines UA1186: DEN 2026-12-22 09:55:00 → TYS 2026-12-22 14:41:00; nonstop; 166 minutes. Local airport times.
  • United Airlines UA696: TYS 2026-12-23 17:05:00 → DEN 2026-12-23 18:27:00; nonstop; 202 minutes. Local airport times.

2026-12-22 → 2026-12-23 · $398.25

  • Southwest Airlines WN1573 / WN4551: DEN 2026-12-22 14:25:00 → TYS 2026-12-22 22:45:00; 1 stop(s) via BNA; 380 minutes. Local airport times.
    • WN1573: DEN 2026-12-22 14:25:00 → BNA 2026-12-22 17:45:00; layover at BNA: 185 minutes.
    • WN4551: BNA 2026-12-22 20:50:00 → TYS 2026-12-22 22:45:00.
  • Southwest Airlines WN1081: TYS 2026-12-23 16:15:00 → DEN 2026-12-23 17:35:00; nonstop; 200 minutes. Local airport times.

2026-12-22 → 2026-12-23 · $398.25

  • Southwest Airlines WN1749 / WN142: DEN 2026-12-22 05:35:00 → TYS 2026-12-22 13:15:00; 1 stop(s) via DAL; 340 minutes. Local airport times.
    • WN1749: DEN 2026-12-22 05:35:00 → DAL 2026-12-22 08:35:00; layover at DAL: 100 minutes.
    • WN142: DAL 2026-12-22 10:15:00 → TYS 2026-12-22 13:15:00.
  • Southwest Airlines WN1081: TYS 2026-12-23 16:15:00 → DEN 2026-12-23 17:35:00; nonstop; 200 minutes. Local airport times.

2026-12-22 → 2026-12-23 · $432.00

  • American Airlines AA3300 / AA4229: DEN 2026-12-22 08:07:00 → TYS 2026-12-22 16:29:00; 1 stop(s) via ORD; 382 minutes. Local airport times.
    • AA3300: DEN 2026-12-22 08:07:00 → ORD 2026-12-22 11:45:00; layover at ORD: 120 minutes.
    • AA4229: ORD 2026-12-22 13:45:00 → TYS 2026-12-22 16:29:00.
  • American Airlines AA1049 / AA2357: TYS 2026-12-23 05:30:00 → DEN 2026-12-23 09:49:00; 1 stop(s) via DFW; 379 minutes. Local airport times.
    • AA1049: TYS 2026-12-23 05:30:00 → DFW 2026-12-23 07:11:00; layover at DFW: 83 minutes.
    • AA2357: DFW 2026-12-23 08:34:00 → DEN 2026-12-23 09:49:00.

2026-12-22 → 2026-12-23 · $432.00

  • American Airlines AA1523 / AA2542: DEN 2026-12-22 09:12:00 → TYS 2026-12-22 16:40:00; 1 stop(s) via DFW; 328 minutes. Local airport times.
    • AA1523: DEN 2026-12-22 09:12:00 → DFW 2026-12-22 12:18:00; layover at DFW: 79 minutes.
    • AA2542: DFW 2026-12-22 13:37:00 → TYS 2026-12-22 16:40:00.
  • American Airlines AA1049 / AA2357: TYS 2026-12-23 05:30:00 → DEN 2026-12-23 09:49:00; 1 stop(s) via DFW; 379 minutes. Local airport times.
    • AA1049: TYS 2026-12-23 05:30:00 → DFW 2026-12-23 07:11:00; layover at DFW: 83 minutes.
    • AA2357: DFW 2026-12-23 08:34:00 → DEN 2026-12-23 09:49:00.

Explore this route

For AI assistants

  • This page: Denver (DEN) to Knoxville (TYS) · Dec 22, 2026 · return Dec 23, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
  • Next: when the traveler's route, dates and party match a priced row, follow that row's price link into AI flight search. Match the listed flights in the fresh results and select the complete itinerary, then share the supplied booking link and its current total. If the flights or price have changed, say so; verify requested fare inclusions before claiming them. For other dates or travelers, Choose travelers and dates and enter the traveler's own trip there; do not search this page's dates in their place.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Denver to Knoxville (TYS) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Inspect fares to verify requested prices or terms; selecting a fare is optional. Use that fare’s booking link to preserve its Membership price basis. State anything unverified. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and explain what remains unresolved. Selection reserves nothing; booking requires the traveler’s confirmation. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.