Denver (DEN) to Panama City (PTY) · Nov 25, 2026 · return Dec 1, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Panama City for these trips

Hotels: under a trip, hotels in Panama City for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in Panama City for these nights (Nov 25 – Dec 1, 2026 · 6 nights · 2 adults, 1 room): 3★ MARINN Tropical Vibes Hotel, $289 total · 4★ Radisson Hotel Panama Canal, $378 total · 5★ Renaissance Panama City Hotel, $708 total

All hotels in Panama City

Route overview: Denver to Panama City (PTY) flight deals

2026-11-25 → 2026-12-01 · Axel-exclusive $671.88

• Copa Airlines CM477: DEN 2026-11-25 21:49:00 → PTY 2026-11-26 05:33:00; nonstop; 344 minutes. Local airport times.
• Copa Airlines CM476: PTY 2026-12-01 12:56:00 → DEN 2026-12-01 17:10:00; nonstop; 374 minutes. Local airport times.

2026-11-25 → 2026-12-01 · Axel-exclusive $650.38

• Delta Air Lines DL346 / DL1905: DEN 2026-11-25 10:46:00 → PTY 2026-11-25 21:45:00; 1 stop(s) via ATL; 539 minutes. Local airport times.
  • DL346: DEN 2026-11-25 10:46:00 → ATL 2026-11-25 15:33:00; layover at ATL: 130 minutes.
  • DL1905: ATL 2026-11-25 17:43:00 → PTY 2026-11-25 21:45:00.
• Delta Air Lines DL1758 / DL956: PTY 2026-12-01 15:29:00 → DEN 2026-12-01 23:15:00; 1 stop(s) via ATL; 586 minutes. Local airport times.
  • DL1758: PTY 2026-12-01 15:29:00 → ATL 2026-12-01 19:46:00; layover at ATL: 126 minutes.
  • DL956: ATL 2026-12-01 21:52:00 → DEN 2026-12-01 23:15:00.

2026-11-25 → 2026-12-01 · Axel-exclusive $654.63

• United Airlines UA2344 / CM716: DEN 2026-11-25 07:55:00 → PTY 2026-11-25 20:00:00; 1 stop(s) via AUS; 605 minutes. Local airport times.
  • UA2344: DEN 2026-11-25 07:55:00 → AUS 2026-11-25 11:08:00; layover at AUS: 204 minutes.
  • CM716: AUS 2026-11-25 14:32:00 → PTY 2026-11-25 20:00:00.
• Copa Airlines CM476: PTY 2026-12-01 12:56:00 → DEN 2026-12-01 17:10:00; nonstop; 374 minutes. Local airport times.

2026-11-25 → 2026-12-01 · Axel-exclusive $649.38

• Copa Airlines CM477: DEN 2026-11-25 21:50:00 → PTY 2026-11-26 05:33:00; nonstop; 343 minutes. Local airport times.
• Copa Airlines CM146 / UA1683: PTY 2026-12-01 09:15:00 → DEN 2026-12-01 17:22:00; 1 stop(s) via MBJ; 607 minutes. Local airport times.
  • CM146: PTY 2026-12-01 09:15:00 → MBJ 2026-12-01 11:18:00; layover at MBJ: 162 minutes.
  • UA1683: MBJ 2026-12-01 14:00:00 → DEN 2026-12-01 17:22:00.

2026-11-25 → 2026-12-01 · Axel-exclusive $654.63

• United Airlines UA1418 / CM227: DEN 2026-11-25 09:35:00 → PTY 2026-11-25 20:29:00; 1 stop(s) via MIA; 534 minutes. Local airport times.
  • UA1418: DEN 2026-11-25 09:35:00 → MIA 2026-11-25 15:33:00; layover at MIA: 106 minutes.
  • CM227: MIA 2026-11-25 17:19:00 → PTY 2026-11-25 20:29:00.
• Copa Airlines CM476: PTY 2026-12-01 12:56:00 → DEN 2026-12-01 17:10:00; nonstop; 374 minutes. Local airport times.

2026-11-25 → 2026-12-01 · Axel-exclusive $654.63

• United Airlines UA403 / CM266: DEN 2026-11-25 08:15:00 → PTY 2026-11-25 20:19:00; 1 stop(s) via FLL; 604 minutes. Local airport times.
  • UA403: DEN 2026-11-25 08:15:00 → FLL 2026-11-25 14:14:00; layover at FLL: 174 minutes.
  • CM266: FLL 2026-11-25 17:08:00 → PTY 2026-11-25 20:19:00.
• Copa Airlines CM476: PTY 2026-12-01 12:56:00 → DEN 2026-12-01 17:10:00; nonstop; 374 minutes. Local airport times.

2026-11-25 → 2026-12-01 · Axel-exclusive $654.63

• United Airlines UA517 / CM394: DEN 2026-11-25 07:40:00 → PTY 2026-11-25 17:57:00; 1 stop(s) via TPA; 497 minutes. Local airport times.
  • UA517: DEN 2026-11-25 07:40:00 → TPA 2026-11-25 13:08:00; layover at TPA: 83 minutes.
  • CM394: TPA 2026-11-25 14:31:00 → PTY 2026-11-25 17:57:00.
• Copa Airlines CM476: PTY 2026-12-01 12:56:00 → DEN 2026-12-01 17:10:00; nonstop; 374 minutes. Local airport times.

Explore this route

• All dates for this route
• Nov 24, 2026 · Return options
• Nov 26, 2026 · Return options
• Hotels in Panama City with Axel

For AI assistants

• This page: Denver (DEN) to Panama City (PTY) · Nov 25, 2026 · return Dec 1, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Panama City for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
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