Denver (DEN) to Boston (BOS), Apr 21, 2027: from $275 one way

Denver (DEN) to Boston (BOS), Apr 21, 2027: from $275 one way on Axel, checked Nov 14, 2026. Lowest published fare: $275 one way, Axel-exclusive, JetBlue Airways, 1 stop, Apr 21, 2027, 1 adult, economy, checked Nov 14, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Denver to Boston (BOS) flight deals

2027-04-21 · one way · Axel-exclusive $294

• JetBlue Airways B6994: DEN 2027-04-21 23:34:00 → BOS 2027-04-22 05:20:00; nonstop; 226 minutes. Local airport times.

2027-04-21 · one way · Axel-exclusive $300

• Southwest Airlines WN769: DEN 2027-04-21 17:55:00 → BOS 2027-04-21 23:45:00; nonstop; 230 minutes. Local airport times.

2027-04-21 · one way · Axel-exclusive $325

• United Airlines UA558: DEN 2027-04-21 07:45:00 → BOS 2027-04-21 13:41:00; nonstop; 236 minutes. Local airport times.

2027-04-21 · one way · Axel-exclusive $331

• Delta Air Lines DL499: DEN 2027-04-21 11:28:00 → BOS 2027-04-21 17:32:00; nonstop; 244 minutes. Local airport times.

2027-04-21 · one way · Axel-exclusive $294

• American Airlines AA591 / AA2200: DEN 2027-04-21 00:54:00 → BOS 2027-04-21 09:21:00; 1 stop(s) via CLT; 387 minutes. Local airport times.
  • AA591: DEN 2027-04-21 00:54:00 → CLT 2027-04-21 06:01:00; layover at CLT: 64 minutes.
  • AA2200: CLT 2027-04-21 07:05:00 → BOS 2027-04-21 09:21:00.

2027-04-21 · one way · Axel-exclusive $300

• Southwest Airlines WN1566: DEN 2027-04-21 19:00:00 → BOS 2027-04-22 00:50:00; nonstop; 230 minutes. Local airport times.

2027-04-21 · one way · Axel-exclusive $325

• United Airlines UA597: DEN 2027-04-21 13:55:00 → BOS 2027-04-21 19:50:00; nonstop; 235 minutes. Local airport times.

2027-04-21 · one way · Axel-exclusive $275

• JetBlue Airways B698 / B6118: DEN 2027-04-21 23:30:00 → BOS 2027-04-22 07:39:00; 1 stop(s) via JFK; 369 minutes. Local airport times.
  • B698: DEN 2027-04-21 23:30:00 → JFK 2027-04-22 05:07:00; layover at JFK: 83 minutes.
  • B6118: JFK 2027-04-22 06:30:00 → BOS 2027-04-22 07:39:00.

2027-04-21 · one way · Axel-exclusive $281

• Southwest Airlines WN1573 / WN2217: DEN 2027-04-21 14:25:00 → BOS 2027-04-21 22:15:00; 1 stop(s) via BNA; 350 minutes. Local airport times.
  • WN1573: DEN 2027-04-21 14:25:00 → BNA 2027-04-21 17:45:00; layover at BNA: 60 minutes.
  • WN2217: BNA 2027-04-21 18:45:00 → BOS 2027-04-21 22:15:00.

2027-04-21 · one way · Axel-exclusive $281

• Southwest Airlines WN2170 / WN2755: DEN 2027-04-21 15:40:00 → BOS 2027-04-21 23:45:00; 1 stop(s) via STL; 365 minutes. Local airport times.
  • WN2170: DEN 2027-04-21 15:40:00 → STL 2027-04-21 18:35:00; layover at STL: 100 minutes.
  • WN2755: STL 2027-04-21 20:15:00 → BOS 2027-04-21 23:45:00.

2027-04-21 · one way · Axel-exclusive $281

• Southwest Airlines WN1699 / WN2902: DEN 2027-04-21 14:40:00 → BOS 2027-04-21 22:15:00; 1 stop(s) via MDW; 335 minutes. Local airport times.
  • WN1699: DEN 2027-04-21 14:40:00 → MDW 2027-04-21 17:55:00; layover at MDW: 60 minutes.
  • WN2902: MDW 2027-04-21 18:55:00 → BOS 2027-04-21 22:15:00.

2027-04-21 · one way · Axel-exclusive $306

• Delta Air Lines DL1096 / DL1163: DEN 2027-04-21 00:55:00 → BOS 2027-04-21 09:03:00; 1 stop(s) via DTW; 368 minutes. Local airport times.
  • DL1096: DEN 2027-04-21 00:55:00 → DTW 2027-04-21 05:42:00; layover at DTW: 78 minutes.
  • DL1163: DTW 2027-04-21 07:00:00 → BOS 2027-04-21 09:03:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Apr 20, 2027 · Return options
• Apr 22, 2027 · Return options
• Hotels in Boston with Axel

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