Columbus (CMH) to Saint Louis (STL), Nov 19, 2026: from $150 one way

Columbus (CMH) to Saint Louis (STL), Nov 19, 2026: from $150 one way on Axel, checked Oct 29, 2026. Lowest published fare: $150 one way, Axel-exclusive, Southwest Airlines, nonstop, Nov 19, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Columbus to Saint Louis (STL) flight deals

2026-11-19 · one way · Axel-exclusive $150.00

• Southwest Airlines WN1282: CMH 2026-11-19 20:30:00 → STL 2026-11-19 21:00:00; nonstop; 90 minutes. Local airport times.

2026-11-19 · one way · Axel-exclusive $175.00

• American Airlines AA3572 / AA6332: CMH 2026-11-19 08:11:00 → STL 2026-11-19 12:55:00; 1 stop(s) via ORD; 344 minutes. Local airport times.
  • AA3572: CMH 2026-11-19 08:11:00 → ORD 2026-11-19 09:00:00; layover at ORD: 146 minutes.
  • AA6332: ORD 2026-11-19 11:26:00 → STL 2026-11-19 12:55:00.

2026-11-19 · one way · Axel-exclusive $180.00

• United Airlines UA1139 / UA4412: CMH 2026-11-19 14:15:00 → STL 2026-11-19 19:28:00; 1 stop(s) via ORD; 373 minutes. Local airport times.
  • UA1139: CMH 2026-11-19 14:15:00 → ORD 2026-11-19 14:45:00; layover at ORD: 185 minutes.
  • UA4412: ORD 2026-11-19 17:50:00 → STL 2026-11-19 19:28:00.

2026-11-19 · one way · Axel-exclusive $185.00

• Delta Air Lines DL5774 / DL2822: CMH 2026-11-19 14:11:00 → STL 2026-11-19 17:20:00; 1 stop(s) via DTW; 249 minutes. Local airport times.
  • DL5774: CMH 2026-11-19 14:11:00 → DTW 2026-11-19 15:17:00; layover at DTW: 76 minutes.
  • DL2822: DTW 2026-11-19 16:33:00 → STL 2026-11-19 17:20:00.

2026-11-19 · one way · Axel-exclusive $150.00

• Southwest Airlines WN1281: CMH 2026-11-19 06:45:00 → STL 2026-11-19 07:20:00; nonstop; 95 minutes. Local airport times.

2026-11-19 · one way · Axel-exclusive $160.00

• Southwest Airlines WN1339 / WN2043: CMH 2026-11-19 21:05:00 → STL 2026-11-19 23:55:00; 1 stop(s) via BNA; 230 minutes. Local airport times.
  • WN1339: CMH 2026-11-19 21:05:00 → BNA 2026-11-19 21:30:00; layover at BNA: 70 minutes.
  • WN2043: BNA 2026-11-19 22:40:00 → STL 2026-11-19 23:55:00.

2026-11-19 · one way · Axel-exclusive $160.00

• Southwest Airlines WN1718 / WN2339: CMH 2026-11-19 19:30:00 → STL 2026-11-19 22:00:00; 1 stop(s) via MDW; 210 minutes. Local airport times.
  • WN1718: CMH 2026-11-19 19:30:00 → MDW 2026-11-19 19:40:00; layover at MDW: 65 minutes.
  • WN2339: MDW 2026-11-19 20:45:00 → STL 2026-11-19 22:00:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 18, 2026 · Return options
• Nov 20, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Columbus (CMH) to Saint Louis (STL) · Nov 19, 2026 · one way: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
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