Charlotte (CLT) to Knoxville (TYS), Nov 22–23, 2026: from $320 round trip

Charlotte (CLT) to Knoxville (TYS), Nov 22–23, 2026: from $320 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $320 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 22–23, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Charlotte to Knoxville (TYS) flight deals

2026-11-22 → 2026-11-23 · Axel-exclusive $340.00

• American Airlines AA5292: CLT 2026-11-22 21:35:00 → TYS 2026-11-22 22:48:00; nonstop; 73 minutes. Local airport times.
• American Airlines AA5118: TYS 2026-11-23 08:50:00 → CLT 2026-11-23 10:17:00; nonstop; 87 minutes. Local airport times.

2026-11-22 → 2026-11-23 · Axel-exclusive $320.00

• Southwest Airlines WN1225 / WN1875: CLT 2026-11-22 06:40:00 → TYS 2026-11-22 12:20:00; 1 stop(s) via BNA; 340 minutes. Local airport times.
  • WN1225: CLT 2026-11-22 06:40:00 → BNA 2026-11-22 07:10:00; layover at BNA: 190 minutes.
  • WN1875: BNA 2026-11-22 10:20:00 → TYS 2026-11-22 12:20:00.
• Southwest Airlines WN463 / WN4582: TYS 2026-11-23 17:15:00 → CLT 2026-11-23 21:05:00; 1 stop(s) via BNA; 230 minutes. Local airport times.
  • WN463: TYS 2026-11-23 17:15:00 → BNA 2026-11-23 17:15:00; layover at BNA: 75 minutes.
  • WN4582: BNA 2026-11-23 18:30:00 → CLT 2026-11-23 21:05:00.

2026-11-22 → 2026-11-23 · Axel-exclusive $380.00

• Delta Air Lines DL1656 / DL4666: CLT 2026-11-22 06:30:00 → TYS 2026-11-22 10:01:00; 1 stop(s) via ATL; 211 minutes. Local airport times.
  • DL1656: CLT 2026-11-22 06:30:00 → ATL 2026-11-22 07:55:00; layover at ATL: 60 minutes.
  • DL4666: ATL 2026-11-22 08:55:00 → TYS 2026-11-22 10:01:00.
• Delta Air Lines DL4666 / DL3031: TYS 2026-11-23 10:35:00 → CLT 2026-11-23 16:08:00; 1 stop(s) via ATL; 333 minutes. Local airport times.
  • DL4666: TYS 2026-11-23 10:35:00 → ATL 2026-11-23 11:36:00; layover at ATL: 202 minutes.
  • DL3031: ATL 2026-11-23 14:58:00 → CLT 2026-11-23 16:08:00.

2026-11-22 → 2026-11-23 · Axel-exclusive $340.00

• American Airlines AA6018: CLT 2026-11-22 09:10:00 → TYS 2026-11-22 10:33:00; nonstop; 83 minutes. Local airport times.
• American Airlines AA5118: TYS 2026-11-23 08:50:00 → CLT 2026-11-23 10:17:00; nonstop; 87 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 21, 2026 · Return options
• Nov 23, 2026 · Return options
• Hotels in Knoxville with Axel

For AI assistants

• This page: Charlotte (CLT) to Knoxville (TYS) · Nov 22, 2026 · return Nov 23, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
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