Travel with Axel,
get the best price.

Route overview: Charleston to Minneapolis (MSP) flight deals

Charleston → Minneapolis

Dec 21, 2026 · return Dec 29, 2026

CHS → MSP1 adulteconomyRound trip

7 flight options · 4 airlines

Nonstop flights

Mon, Dec 21 – Tue, Dec 29

Delta Air Lines
3:14 pmCHS
3h 11m
Nonstop
5:25 pmMSP
Delta Air Lines
10:22 amMSP
2h 55m
Nonstop
2:17 pmCHS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

One-stop flights

Mon, Dec 21 – Tue, Dec 29

Southwest Airlines
1:20 pmCHS
4h 55m
BNA · 1h 5m
5:15 pmMSP
Southwest Airlines
5:40 pmMSP
5h 35m
BNA · 1h 55m
12:15 am+1CHS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Dec 21 – Tue, Dec 29

American Airlines
6:00 amCHS
5h 53m
DCA · 1h 16m
10:53 amMSP
American Airlines
3:47 pmMSP
5h 21m
ORD · 1h 21m
10:08 pmCHS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Dec 21 – Tue, Dec 29

United Airlines
5:00 pmCHS
5h 38m
ORD · 1h 19m
9:38 pmMSP
United Airlines
11:55 amMSP
6h 20m
IAD · 1h 49m
7:15 pmCHS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Dec 21 – Tue, Dec 29

Southwest Airlines
7:20 amCHS
5h 55m
BWI · 1h 45m
12:15 pmMSP
Southwest Airlines
5:40 pmMSP
5h 35m
BNA · 1h 55m
12:15 am+1CHS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Dec 21 – Tue, Dec 29

Delta Air Lines
12:55 pmCHS
5h 10m
ATL · 1h 19m
5:05 pmMSP
Delta Air Lines
10:22 amMSP
2h 55m
Nonstop
2:17 pmCHS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Mon, Dec 21 – Tue, Dec 29

Delta Air Lines
3:23 pmCHS
3h
Nonstop
5:23 pmMSP
Delta Air Lines
6:00 amMSP
5h 26m
DTW · 1h 27m
12:26 pmCHS

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Make this trip yours

CHS ⇄ MSP

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

No account needed to see prices.

Already have an account? Log in

Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Delta Air Lines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • Not satisfied? Full refund.If you are unhappy with the experience for any reason, or simply change your mind, cancel within 24 hours of booking (departure 7+ days away) and we refund you in full. We stand by our product. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

Explore this route

For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-21 → 2026-12-29Delta Air LinesDL2463 / DL2463Axel-exclusive $465.382026-10-29T00:55:55Z
2026-12-21 → 2026-12-29Southwest AirlinesWN4634 + WN611 / WN3118 + WN746Axel-exclusive $382.502026-10-29T00:55:55Z
2026-12-21 → 2026-12-29American AirlinesAA1015 + AA5127 / AA2366 + AA1082Axel-exclusive $401.632026-10-29T00:55:55Z
2026-12-21 → 2026-12-29United AirlinesUA291 + UA2005 / UA3579 + UA3526Axel-exclusive $414.382026-10-29T00:55:55Z
2026-12-21 → 2026-12-29Southwest AirlinesWN4375 + WN3102 / WN3118 + WN746Axel-exclusive $382.502026-10-29T00:55:55Z
2026-12-21 → 2026-12-29Delta Air LinesDL1437 + DL2981 / DL2463Axel-exclusive $445.882026-10-29T00:55:55Z
2026-12-21 → 2026-12-29Delta Air LinesDL2463 / DL1461 + DL5017Axel-exclusive $446.632026-10-29T00:55:55Z

Route overview: Charleston to Minneapolis (MSP) flight deals

2026-12-21 → 2026-12-29 · Axel-exclusive $465.38

  • Delta Air Lines DL2463: CHS 2026-12-21 15:14:00 → MSP 2026-12-21 17:25:00; nonstop; 191 minutes. Local airport times.
  • Delta Air Lines DL2463: MSP 2026-12-29 10:22:00 → CHS 2026-12-29 14:17:00; nonstop; 175 minutes. Local airport times.

2026-12-21 → 2026-12-29 · Axel-exclusive $382.50

  • Southwest Airlines WN4634 / WN611: CHS 2026-12-21 13:20:00 → MSP 2026-12-21 17:15:00; 1 stop(s) via BNA; 295 minutes. Local airport times.
    • WN4634: CHS 2026-12-21 13:20:00 → BNA 2026-12-21 14:00:00; layover at BNA: 65 minutes.
    • WN611: BNA 2026-12-21 15:05:00 → MSP 2026-12-21 17:15:00.
  • Southwest Airlines WN3118 / WN746: MSP 2026-12-29 17:40:00 → CHS 2026-12-30 00:15:00; 1 stop(s) via BNA; 335 minutes. Local airport times.
    • WN3118: MSP 2026-12-29 17:40:00 → BNA 2026-12-29 19:50:00; layover at BNA: 115 minutes.
    • WN746: BNA 2026-12-29 21:45:00 → CHS 2026-12-30 00:15:00.

2026-12-21 → 2026-12-29 · Axel-exclusive $401.63

  • American Airlines AA1015 / AA5127: CHS 2026-12-21 06:00:00 → MSP 2026-12-21 10:53:00; 1 stop(s) via DCA; 353 minutes. Local airport times.
    • AA1015: CHS 2026-12-21 06:00:00 → DCA 2026-12-21 07:32:00; layover at DCA: 76 minutes.
    • AA5127: DCA 2026-12-21 08:48:00 → MSP 2026-12-21 10:53:00.
  • American Airlines AA2366 / AA1082: MSP 2026-12-29 15:47:00 → CHS 2026-12-29 22:08:00; 1 stop(s) via ORD; 321 minutes. Local airport times.
    • AA2366: MSP 2026-12-29 15:47:00 → ORD 2026-12-29 17:29:00; layover at ORD: 81 minutes.
    • AA1082: ORD 2026-12-29 18:50:00 → CHS 2026-12-29 22:08:00.

2026-12-21 → 2026-12-29 · Axel-exclusive $414.38

  • United Airlines UA291 / UA2005: CHS 2026-12-21 17:00:00 → MSP 2026-12-21 21:38:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
    • UA291: CHS 2026-12-21 17:00:00 → ORD 2026-12-21 18:36:00; layover at ORD: 79 minutes.
    • UA2005: ORD 2026-12-21 19:55:00 → MSP 2026-12-21 21:38:00.
  • United Airlines UA3579 / UA3526: MSP 2026-12-29 11:55:00 → CHS 2026-12-29 19:15:00; 1 stop(s) via IAD; 380 minutes. Local airport times.
    • UA3579: MSP 2026-12-29 11:55:00 → IAD 2026-12-29 15:26:00; layover at IAD: 109 minutes.
    • UA3526: IAD 2026-12-29 17:15:00 → CHS 2026-12-29 19:15:00.

2026-12-21 → 2026-12-29 · Axel-exclusive $382.50

  • Southwest Airlines WN4375 / WN3102: CHS 2026-12-21 07:20:00 → MSP 2026-12-21 12:15:00; 1 stop(s) via BWI; 355 minutes. Local airport times.
    • WN4375: CHS 2026-12-21 07:20:00 → BWI 2026-12-21 08:50:00; layover at BWI: 105 minutes.
    • WN3102: BWI 2026-12-21 10:35:00 → MSP 2026-12-21 12:15:00.
  • Southwest Airlines WN3118 / WN746: MSP 2026-12-29 17:40:00 → CHS 2026-12-30 00:15:00; 1 stop(s) via BNA; 335 minutes. Local airport times.
    • WN3118: MSP 2026-12-29 17:40:00 → BNA 2026-12-29 19:50:00; layover at BNA: 115 minutes.
    • WN746: BNA 2026-12-29 21:45:00 → CHS 2026-12-30 00:15:00.

2026-12-21 → 2026-12-29 · Axel-exclusive $445.88

  • Delta Air Lines DL1437 / DL2981: CHS 2026-12-21 12:55:00 → MSP 2026-12-21 17:05:00; 1 stop(s) via ATL; 310 minutes. Local airport times.
    • DL1437: CHS 2026-12-21 12:55:00 → ATL 2026-12-21 14:09:00; layover at ATL: 79 minutes.
    • DL2981: ATL 2026-12-21 15:28:00 → MSP 2026-12-21 17:05:00.
  • Delta Air Lines DL2463: MSP 2026-12-29 10:22:00 → CHS 2026-12-29 14:17:00; nonstop; 175 minutes. Local airport times.

2026-12-21 → 2026-12-29 · Axel-exclusive $446.63

  • Delta Air Lines DL2463: CHS 2026-12-21 15:23:00 → MSP 2026-12-21 17:23:00; nonstop; 180 minutes. Local airport times.
  • Delta Air Lines DL1461 / DL5017: MSP 2026-12-29 06:00:00 → CHS 2026-12-29 12:26:00; 1 stop(s) via DTW; 326 minutes. Local airport times.
    • DL1461: MSP 2026-12-29 06:00:00 → DTW 2026-12-29 08:48:00; layover at DTW: 87 minutes.
    • DL5017: DTW 2026-12-29 10:15:00 → CHS 2026-12-29 12:26:00.

Explore this route

For AI assistants

  • This page: Charleston (CHS) to Minneapolis (MSP) · Dec 21, 2026 · return Dec 29, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
  • Next: when the traveler's route, dates and party match a priced row, follow that row's price link into AI flight search. Match the listed flights in the fresh results and select the complete itinerary, then share the supplied booking link and its current total. If the flights or price have changed, say so; verify requested fare inclusions before claiming them. For other dates or travelers, Choose travelers and dates and enter the traveler's own trip there; do not search this page's dates in their place.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Charleston to Minneapolis (MSP) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.