Travel with Axel,
get the best price.

Charleston → Rome

Choose your travel dates

CHS → FCO1 adulteconomy

18 flight options · 2 airlines

Round-trip flights

Fri, Nov 20 – Mon, Nov 23

United Airlines
2:52 pmCHS
11h 38m
IAD · 1h 35m
8:30 am+1FCO
United Airlines
11:00 amFCO
14h 11m
IAD · 2h 10m
7:11 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
12:55 pmCHS
13h 20m
ATL · 2h 46m
8:15 am+1FCO
Delta Air Lines
11:45 amFCO
14h 34m
JFK · 2h 8m
8:19 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
12:15 pmCHS
13h 30m
ORD · 1h 43m
7:45 am+1FCO
United Airlines
11:00 amFCO
14h 11m
IAD · 2h 10m
7:11 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
3:30 pmCHS
13h 25m
EWR · 2h 49m
10:55 am+1FCO
United Airlines
11:00 amFCO
14h 11m
IAD · 2h 10m
7:11 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
12:15 pmCHS
13h 30m
ORD · 1h 43m
7:45 am+1FCO
United Airlines
11:00 amFCO
14h 11m
IAD · 2h 10m
7:11 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
12:24 pmCHS
13h 21m
JFK · 2h 54m
7:45 am+1FCO
Delta Air Lines
11:45 amFCO
14h 34m
JFK · 2h 8m
8:19 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
2:50 pmCHS
11h 55m
BOS · 1h 28m
8:45 am+1FCO
Delta Air Lines
11:45 amFCO
14h 34m
JFK · 2h 8m
8:19 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
3:30 pmCHS
13h 25m
EWR · 2h 49m
10:55 am+1FCO
United Airlines
11:00 amFCO
14h 11m
IAD · 2h 10m
7:11 pmCHS

Round-trip total · 1 adult · Taxes included

Show 4 more flights

Fri, Nov 27 – Fri, Dec 4

United Airlines
2:52 pmCHS
11h 38m
IAD · 1h 35m
8:30 am+1FCO
United Airlines
11:00 amFCO
14h 11m
IAD · 2h 10m
7:11 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
12:24 pmCHS
13h 21m
JFK · 2h 54m
7:45 am+1FCO
Delta Air Lines
11:45 amFCO
14h 34m
JFK · 2h 8m
8:19 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
12:55 pmCHS
13h 20m
ATL · 2h 46m
8:15 am+1FCO
Delta Air Lines
11:45 amFCO
14h 34m
JFK · 2h 8m
8:19 pmCHS

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
2:50 pmCHS
11h 55m
BOS · 1h 28m
8:45 am+1FCO
Delta Air Lines
11:45 amFCO
14h 34m
JFK · 2h 8m
8:19 pmCHS

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

United Airlines
3:30 pmCHS
13h 25m
EWR · 2h 49m
10:55 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
12:24 pmCHS
13h 21m
JFK · 2h 54m
7:45 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
2:52 pmCHS
11h 38m
IAD · 1h 35m
8:30 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
12:15 pmCHS
13h 30m
ORD · 1h 43m
7:45 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
2:50 pmCHS
11h 55m
BOS · 1h 28m
8:45 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
12:55 pmCHS
13h 20m
ATL · 2h 46m
8:15 am+1FCO

One-way total · 1 adult · Taxes included

Make this trip yours

CHS ⇄ FCO

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

No account needed to see prices.

Already have an account? Log in

Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, United Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one wayUnited AirlinesUA2693 + UA510$655.502026-10-29T00:55:37Z
2026-11-20 · one wayDelta Air LinesDL5015 + DL182$674.502026-10-29T00:55:37Z
2026-11-20 → 2026-11-23United AirlinesUA2786 + UA884 / UA885 + UA3632$921.502026-10-29T00:55:37Z
2026-11-20 → 2026-11-23Delta Air LinesDL1437 + DL214 / DL183 + DL5293$940.502026-10-29T00:55:37Z
2026-11-27 → 2026-12-04United AirlinesUA5461 + UA970 / UA885 + UA3632$945.752026-10-29T00:55:37Z
2026-11-20 · one wayUnited AirlinesUA2786 + UA884$655.502026-10-29T00:55:37Z
2026-11-20 · one wayUnited AirlinesUA5461 + UA970$655.502026-10-29T00:55:37Z
2026-11-20 · one wayDelta Air LinesDL2785 + DL112$674.502026-10-29T00:55:37Z
2026-11-20 · one wayDelta Air LinesDL1437 + DL214$674.502026-10-29T00:55:37Z
2026-11-20 → 2026-11-23United AirlinesUA2693 + UA510 / UA885 + UA3632$921.502026-10-29T00:55:37Z
2026-11-20 → 2026-11-23United AirlinesUA5461 + UA970 / UA885 + UA3632$921.502026-10-29T00:55:37Z
2026-11-20 → 2026-11-23Delta Air LinesDL5015 + DL182 / DL183 + DL5293$940.502026-10-29T00:55:37Z
2026-11-20 → 2026-11-23Delta Air LinesDL2785 + DL112 / DL183 + DL5293$940.502026-10-29T00:55:37Z
2026-11-27 → 2026-12-04United AirlinesUA2693 + UA510 / UA885 + UA3632$945.752026-10-29T00:55:37Z
2026-11-27 → 2026-12-04United AirlinesUA2786 + UA884 / UA885 + UA3632$945.752026-10-29T00:55:37Z
2026-11-27 → 2026-12-04Delta Air LinesDL5015 + DL182 / DL183 + DL5293$965.252026-10-29T00:55:37Z
2026-11-27 → 2026-12-04Delta Air LinesDL1437 + DL214 / DL183 + DL5293$965.252026-10-29T00:55:37Z
2026-11-27 → 2026-12-04Delta Air LinesDL2785 + DL112 / DL183 + DL5293$965.252026-10-29T00:55:37Z

2026-11-20 · one way · $655.50

  • United Airlines UA2693 / UA510: CHS 2026-11-20 15:30:00 → FCO 2026-11-21 10:55:00; 1 stop(s) via EWR; 805 minutes. Local airport times.
    • UA2693: CHS 2026-11-20 15:30:00 → EWR 2026-11-20 17:31:00; layover at EWR: 169 minutes.
    • UA510: EWR 2026-11-20 20:20:00 → FCO 2026-11-21 10:55:00.

2026-11-20 · one way · $674.50

  • Delta Air Lines DL5015 / DL182: CHS 2026-11-20 12:24:00 → FCO 2026-11-21 07:45:00; 1 stop(s) via JFK; 801 minutes. Local airport times.
    • DL5015: CHS 2026-11-20 12:24:00 → JFK 2026-11-20 14:31:00; layover at JFK: 174 minutes.
    • DL182: JFK 2026-11-20 17:25:00 → FCO 2026-11-21 07:45:00.

2026-11-20 → 2026-11-23 · $921.50

  • United Airlines UA2786 / UA884: CHS 2026-11-20 14:52:00 → FCO 2026-11-21 08:30:00; 1 stop(s) via IAD; 698 minutes. Local airport times.
    • UA2786: CHS 2026-11-20 14:52:00 → IAD 2026-11-20 16:25:00; layover at IAD: 95 minutes.
    • UA884: IAD 2026-11-20 18:00:00 → FCO 2026-11-21 08:30:00.
  • United Airlines UA885 / UA3632: FCO 2026-11-23 11:00:00 → CHS 2026-11-23 19:11:00; 1 stop(s) via IAD; 851 minutes. Local airport times.
    • UA885: FCO 2026-11-23 11:00:00 → IAD 2026-11-23 15:05:00; layover at IAD: 130 minutes.
    • UA3632: IAD 2026-11-23 17:15:00 → CHS 2026-11-23 19:11:00.

2026-11-20 → 2026-11-23 · $940.50

  • Delta Air Lines DL1437 / DL214: CHS 2026-11-20 12:55:00 → FCO 2026-11-21 08:15:00; 1 stop(s) via ATL; 800 minutes. Local airport times.
    • DL1437: CHS 2026-11-20 12:55:00 → ATL 2026-11-20 14:09:00; layover at ATL: 166 minutes.
    • DL214: ATL 2026-11-20 16:55:00 → FCO 2026-11-21 08:15:00.
  • Delta Air Lines DL183 / DL5293: FCO 2026-11-23 11:45:00 → CHS 2026-11-23 20:19:00; 1 stop(s) via JFK; 874 minutes. Local airport times.
    • DL183: FCO 2026-11-23 11:45:00 → JFK 2026-11-23 15:47:00; layover at JFK: 128 minutes.
    • DL5293: JFK 2026-11-23 17:55:00 → CHS 2026-11-23 20:19:00.

2026-11-27 → 2026-12-04 · $945.75

  • United Airlines UA5461 / UA970: CHS 2026-11-27 12:15:00 → FCO 2026-11-28 07:45:00; 1 stop(s) via ORD; 810 minutes. Local airport times.
    • UA5461: CHS 2026-11-27 12:15:00 → ORD 2026-11-27 13:57:00; layover at ORD: 103 minutes.
    • UA970: ORD 2026-11-27 15:40:00 → FCO 2026-11-28 07:45:00.
  • United Airlines UA885 / UA3632: FCO 2026-12-04 11:00:00 → CHS 2026-12-04 19:11:00; 1 stop(s) via IAD; 851 minutes. Local airport times.
    • UA885: FCO 2026-12-04 11:00:00 → IAD 2026-12-04 15:05:00; layover at IAD: 130 minutes.
    • UA3632: IAD 2026-12-04 17:15:00 → CHS 2026-12-04 19:11:00.

2026-11-20 · one way · $655.50

  • United Airlines UA2786 / UA884: CHS 2026-11-20 14:52:00 → FCO 2026-11-21 08:30:00; 1 stop(s) via IAD; 698 minutes. Local airport times.
    • UA2786: CHS 2026-11-20 14:52:00 → IAD 2026-11-20 16:25:00; layover at IAD: 95 minutes.
    • UA884: IAD 2026-11-20 18:00:00 → FCO 2026-11-21 08:30:00.

2026-11-20 · one way · $655.50

  • United Airlines UA5461 / UA970: CHS 2026-11-20 12:15:00 → FCO 2026-11-21 07:45:00; 1 stop(s) via ORD; 810 minutes. Local airport times.
    • UA5461: CHS 2026-11-20 12:15:00 → ORD 2026-11-20 13:57:00; layover at ORD: 103 minutes.
    • UA970: ORD 2026-11-20 15:40:00 → FCO 2026-11-21 07:45:00.

2026-11-20 · one way · $674.50

  • Delta Air Lines DL2785 / DL112: CHS 2026-11-20 14:50:00 → FCO 2026-11-21 08:45:00; 1 stop(s) via BOS; 715 minutes. Local airport times.
    • DL2785: CHS 2026-11-20 14:50:00 → BOS 2026-11-20 17:12:00; layover at BOS: 88 minutes.
    • DL112: BOS 2026-11-20 18:40:00 → FCO 2026-11-21 08:45:00.

2026-11-20 · one way · $674.50

  • Delta Air Lines DL1437 / DL214: CHS 2026-11-20 12:55:00 → FCO 2026-11-21 08:15:00; 1 stop(s) via ATL; 800 minutes. Local airport times.
    • DL1437: CHS 2026-11-20 12:55:00 → ATL 2026-11-20 14:09:00; layover at ATL: 166 minutes.
    • DL214: ATL 2026-11-20 16:55:00 → FCO 2026-11-21 08:15:00.

2026-11-20 → 2026-11-23 · $921.50

  • United Airlines UA2693 / UA510: CHS 2026-11-20 15:30:00 → FCO 2026-11-21 10:55:00; 1 stop(s) via EWR; 805 minutes. Local airport times.
    • UA2693: CHS 2026-11-20 15:30:00 → EWR 2026-11-20 17:31:00; layover at EWR: 169 minutes.
    • UA510: EWR 2026-11-20 20:20:00 → FCO 2026-11-21 10:55:00.
  • United Airlines UA885 / UA3632: FCO 2026-11-23 11:00:00 → CHS 2026-11-23 19:11:00; 1 stop(s) via IAD; 851 minutes. Local airport times.
    • UA885: FCO 2026-11-23 11:00:00 → IAD 2026-11-23 15:05:00; layover at IAD: 130 minutes.
    • UA3632: IAD 2026-11-23 17:15:00 → CHS 2026-11-23 19:11:00.

2026-11-20 → 2026-11-23 · $921.50

  • United Airlines UA5461 / UA970: CHS 2026-11-20 12:15:00 → FCO 2026-11-21 07:45:00; 1 stop(s) via ORD; 810 minutes. Local airport times.
    • UA5461: CHS 2026-11-20 12:15:00 → ORD 2026-11-20 13:57:00; layover at ORD: 103 minutes.
    • UA970: ORD 2026-11-20 15:40:00 → FCO 2026-11-21 07:45:00.
  • United Airlines UA885 / UA3632: FCO 2026-11-23 11:00:00 → CHS 2026-11-23 19:11:00; 1 stop(s) via IAD; 851 minutes. Local airport times.
    • UA885: FCO 2026-11-23 11:00:00 → IAD 2026-11-23 15:05:00; layover at IAD: 130 minutes.
    • UA3632: IAD 2026-11-23 17:15:00 → CHS 2026-11-23 19:11:00.

2026-11-20 → 2026-11-23 · $940.50

  • Delta Air Lines DL5015 / DL182: CHS 2026-11-20 12:24:00 → FCO 2026-11-21 07:45:00; 1 stop(s) via JFK; 801 minutes. Local airport times.
    • DL5015: CHS 2026-11-20 12:24:00 → JFK 2026-11-20 14:31:00; layover at JFK: 174 minutes.
    • DL182: JFK 2026-11-20 17:25:00 → FCO 2026-11-21 07:45:00.
  • Delta Air Lines DL183 / DL5293: FCO 2026-11-23 11:45:00 → CHS 2026-11-23 20:19:00; 1 stop(s) via JFK; 874 minutes. Local airport times.
    • DL183: FCO 2026-11-23 11:45:00 → JFK 2026-11-23 15:47:00; layover at JFK: 128 minutes.
    • DL5293: JFK 2026-11-23 17:55:00 → CHS 2026-11-23 20:19:00.

2026-11-20 → 2026-11-23 · $940.50

  • Delta Air Lines DL2785 / DL112: CHS 2026-11-20 14:50:00 → FCO 2026-11-21 08:45:00; 1 stop(s) via BOS; 715 minutes. Local airport times.
    • DL2785: CHS 2026-11-20 14:50:00 → BOS 2026-11-20 17:12:00; layover at BOS: 88 minutes.
    • DL112: BOS 2026-11-20 18:40:00 → FCO 2026-11-21 08:45:00.
  • Delta Air Lines DL183 / DL5293: FCO 2026-11-23 11:45:00 → CHS 2026-11-23 20:19:00; 1 stop(s) via JFK; 874 minutes. Local airport times.
    • DL183: FCO 2026-11-23 11:45:00 → JFK 2026-11-23 15:47:00; layover at JFK: 128 minutes.
    • DL5293: JFK 2026-11-23 17:55:00 → CHS 2026-11-23 20:19:00.

2026-11-27 → 2026-12-04 · $945.75

  • United Airlines UA2693 / UA510: CHS 2026-11-27 15:30:00 → FCO 2026-11-28 10:55:00; 1 stop(s) via EWR; 805 minutes. Local airport times.
    • UA2693: CHS 2026-11-27 15:30:00 → EWR 2026-11-27 17:31:00; layover at EWR: 169 minutes.
    • UA510: EWR 2026-11-27 20:20:00 → FCO 2026-11-28 10:55:00.
  • United Airlines UA885 / UA3632: FCO 2026-12-04 11:00:00 → CHS 2026-12-04 19:11:00; 1 stop(s) via IAD; 851 minutes. Local airport times.
    • UA885: FCO 2026-12-04 11:00:00 → IAD 2026-12-04 15:05:00; layover at IAD: 130 minutes.
    • UA3632: IAD 2026-12-04 17:15:00 → CHS 2026-12-04 19:11:00.

2026-11-27 → 2026-12-04 · $945.75

  • United Airlines UA2786 / UA884: CHS 2026-11-27 14:52:00 → FCO 2026-11-28 08:30:00; 1 stop(s) via IAD; 698 minutes. Local airport times.
    • UA2786: CHS 2026-11-27 14:52:00 → IAD 2026-11-27 16:25:00; layover at IAD: 95 minutes.
    • UA884: IAD 2026-11-27 18:00:00 → FCO 2026-11-28 08:30:00.
  • United Airlines UA885 / UA3632: FCO 2026-12-04 11:00:00 → CHS 2026-12-04 19:11:00; 1 stop(s) via IAD; 851 minutes. Local airport times.
    • UA885: FCO 2026-12-04 11:00:00 → IAD 2026-12-04 15:05:00; layover at IAD: 130 minutes.
    • UA3632: IAD 2026-12-04 17:15:00 → CHS 2026-12-04 19:11:00.

2026-11-27 → 2026-12-04 · $965.25

  • Delta Air Lines DL5015 / DL182: CHS 2026-11-27 12:24:00 → FCO 2026-11-28 07:45:00; 1 stop(s) via JFK; 801 minutes. Local airport times.
    • DL5015: CHS 2026-11-27 12:24:00 → JFK 2026-11-27 14:31:00; layover at JFK: 174 minutes.
    • DL182: JFK 2026-11-27 17:25:00 → FCO 2026-11-28 07:45:00.
  • Delta Air Lines DL183 / DL5293: FCO 2026-12-04 11:45:00 → CHS 2026-12-04 20:19:00; 1 stop(s) via JFK; 874 minutes. Local airport times.
    • DL183: FCO 2026-12-04 11:45:00 → JFK 2026-12-04 15:47:00; layover at JFK: 128 minutes.
    • DL5293: JFK 2026-12-04 17:55:00 → CHS 2026-12-04 20:19:00.

2026-11-27 → 2026-12-04 · $965.25

  • Delta Air Lines DL1437 / DL214: CHS 2026-11-27 12:55:00 → FCO 2026-11-28 08:15:00; 1 stop(s) via ATL; 800 minutes. Local airport times.
    • DL1437: CHS 2026-11-27 12:55:00 → ATL 2026-11-27 14:09:00; layover at ATL: 166 minutes.
    • DL214: ATL 2026-11-27 16:55:00 → FCO 2026-11-28 08:15:00.
  • Delta Air Lines DL183 / DL5293: FCO 2026-12-04 11:45:00 → CHS 2026-12-04 20:19:00; 1 stop(s) via JFK; 874 minutes. Local airport times.
    • DL183: FCO 2026-12-04 11:45:00 → JFK 2026-12-04 15:47:00; layover at JFK: 128 minutes.
    • DL5293: JFK 2026-12-04 17:55:00 → CHS 2026-12-04 20:19:00.

2026-11-27 → 2026-12-04 · $965.25

  • Delta Air Lines DL2785 / DL112: CHS 2026-11-27 14:50:00 → FCO 2026-11-28 08:45:00; 1 stop(s) via BOS; 715 minutes. Local airport times.
    • DL2785: CHS 2026-11-27 14:50:00 → BOS 2026-11-27 17:12:00; layover at BOS: 88 minutes.
    • DL112: BOS 2026-11-27 18:40:00 → FCO 2026-11-28 08:45:00.
  • Delta Air Lines DL183 / DL5293: FCO 2026-12-04 11:45:00 → CHS 2026-12-04 20:19:00; 1 stop(s) via JFK; 874 minutes. Local airport times.
    • DL183: FCO 2026-12-04 11:45:00 → JFK 2026-12-04 15:47:00; layover at JFK: 128 minutes.
    • DL5293: JFK 2026-12-04 17:55:00 → CHS 2026-12-04 20:19:00.

More dates for this route