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Buffalo → Rome

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BUF → FCO1 adulteconomy

15 flight options · 3 airlines

Round-trip flights

Fri, Nov 27 – Fri, Dec 4

American Airlines
3:41 pmBUF
11h 19m
PHL · 1h 23m
9:00 am+1FCO
American Airlines
11:00 amFCO
13h 30m
PHL · 2h 19m
6:30 pmBUF

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
10:42 amBUF
15h 3m
ORD · 3h 41m
7:45 am+1FCO
United Airlines
10:30 amFCO
13h 40m
EWR · 2h 30m
6:10 pmBUF

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
3:20 pmBUF
13h 25m
JFK · 3h 32m
10:45 am+1FCO
Delta Air Lines
10:00 amFCO
15h 13m
DTW · 3h 26m
7:13 pmBUF

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

American Airlines
3:41 pmBUF
11h 19m
PHL · 1h 23m
9:00 am+1FCO
American Airlines
11:00 amFCO
13h 30m
PHL · 2h 19m
6:30 pmBUF

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

United Airlines
3:00 pmBUF
11h 30m
IAD · 1h 15m
8:30 am+1FCO
United Airlines
10:30 amFCO
13h 40m
EWR · 2h 30m
6:10 pmBUF

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
12:11 pmBUF
14h 4m
ATL · 2h 32m
8:15 am+1FCO
Delta Air Lines
10:00 amFCO
15h 13m
DTW · 3h 26m
7:13 pmBUF

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
3:00 pmBUF
11h 30m
IAD · 1h 15m
8:30 am+1FCO
United Airlines
10:30 amFCO
13h 40m
EWR · 2h 30m
6:10 pmBUF

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

United Airlines
10:42 amBUF
15h 3m
ORD · 3h 41m
7:45 am+1FCO
United Airlines
10:30 amFCO
13h 40m
EWR · 2h 30m
6:10 pmBUF

Round-trip total · 1 adult · Taxes included

Show 2 more flights

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
12:11 pmBUF
14h 4m
ATL · 2h 32m
8:15 am+1FCO
Delta Air Lines
10:00 amFCO
15h 13m
DTW · 3h 26m
7:13 pmBUF

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
3:20 pmBUF
13h 25m
JFK · 3h 32m
10:45 am+1FCO
Delta Air Lines
10:00 amFCO
15h 13m
DTW · 3h 26m
7:13 pmBUF

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

American Airlines
3:41 pmBUF
11h 19m
PHL · 1h 23m
9:00 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
10:42 amBUF
15h 3m
ORD · 3h 41m
7:45 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
3:20 pmBUF
13h 25m
JFK · 3h 32m
10:45 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

United Airlines
3:00 pmBUF
11h 30m
IAD · 1h 15m
8:30 am+1FCO

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
12:11 pmBUF
14h 4m
ATL · 2h 32m
8:15 am+1FCO

One-way total · 1 adult · Taxes included

Make this trip yours

BUF ⇄ FCO

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Why book with Axel
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  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
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Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one wayAmerican AirlinesAA5866 + AA718$671.002026-10-29T00:53:59Z
2026-11-20 · one wayUnited AirlinesUA5223 + UA970$687.502026-10-29T00:53:59Z
2026-11-20 · one wayDelta Air LinesDL5296 + DL230$704.002026-10-29T00:53:59Z
2026-11-27 → 2026-12-04American AirlinesAA5866 + AA718 / AA719 + AA5866$913.502026-10-29T00:53:59Z
2026-11-27 → 2026-12-04United AirlinesUA5223 + UA970 / UA41 + UA3607$934.502026-10-29T00:53:59Z
2026-11-27 → 2026-12-04Delta Air LinesDL5296 + DL230 / DL207 + DL3843$955.502026-10-29T00:53:59Z
2026-11-20 → 2026-11-23American AirlinesAA5866 + AA718 / AA719 + AA5866$957.002026-10-29T00:53:59Z
2026-11-20 · one wayUnited AirlinesUA4291 + UA884$687.502026-10-29T00:53:59Z
2026-11-20 · one wayDelta Air LinesDL1384 + DL214$704.002026-10-29T00:53:59Z
2026-11-27 → 2026-12-04United AirlinesUA4291 + UA884 / UA41 + UA3607$934.502026-10-29T00:53:59Z
2026-11-27 → 2026-12-04Delta Air LinesDL1384 + DL214 / DL207 + DL3843$955.502026-10-29T00:53:59Z
2026-11-20 → 2026-11-23United AirlinesUA4291 + UA884 / UA41 + UA3607$979.002026-10-29T00:53:59Z
2026-11-20 → 2026-11-23United AirlinesUA5223 + UA970 / UA41 + UA3607$979.002026-10-29T00:53:59Z
2026-11-20 → 2026-11-23Delta Air LinesDL1384 + DL214 / DL207 + DL3843$1001.002026-10-29T00:53:59Z
2026-11-20 → 2026-11-23Delta Air LinesDL5296 + DL230 / DL207 + DL3843$1001.002026-10-29T00:53:59Z

2026-11-20 · one way · $671.00

  • American Airlines AA5866 / AA718: BUF 2026-11-20 15:41:00 → FCO 2026-11-21 09:00:00; 1 stop(s) via PHL; 679 minutes. Local airport times.
    • AA5866: BUF 2026-11-20 15:41:00 → PHL 2026-11-20 17:17:00; layover at PHL: 83 minutes.
    • AA718: PHL 2026-11-20 18:40:00 → FCO 2026-11-21 09:00:00.

2026-11-20 · one way · $687.50

  • United Airlines UA5223 / UA970: BUF 2026-11-20 10:42:00 → FCO 2026-11-21 07:45:00; 1 stop(s) via ORD; 903 minutes. Local airport times.
    • UA5223: BUF 2026-11-20 10:42:00 → ORD 2026-11-20 11:59:00; layover at ORD: 221 minutes.
    • UA970: ORD 2026-11-20 15:40:00 → FCO 2026-11-21 07:45:00.

2026-11-20 · one way · $704.00

  • Delta Air Lines DL5296 / DL230: BUF 2026-11-20 15:20:00 → FCO 2026-11-21 10:45:00; 1 stop(s) via JFK; 805 minutes. Local airport times.
    • DL5296: BUF 2026-11-20 15:20:00 → JFK 2026-11-20 16:53:00; layover at JFK: 212 minutes.
    • DL230: JFK 2026-11-20 20:25:00 → FCO 2026-11-21 10:45:00.

2026-11-27 → 2026-12-04 · $913.50

  • American Airlines AA5866 / AA718: BUF 2026-11-27 15:41:00 → FCO 2026-11-28 09:00:00; 1 stop(s) via PHL; 679 minutes. Local airport times.
    • AA5866: BUF 2026-11-27 15:41:00 → PHL 2026-11-27 17:17:00; layover at PHL: 83 minutes.
    • AA718: PHL 2026-11-27 18:40:00 → FCO 2026-11-28 09:00:00.
  • American Airlines AA719 / AA5866: FCO 2026-12-04 11:00:00 → BUF 2026-12-04 18:30:00; 1 stop(s) via PHL; 810 minutes. Local airport times.
    • AA719: FCO 2026-12-04 11:00:00 → PHL 2026-12-04 14:40:00; layover at PHL: 139 minutes.
    • AA5866: PHL 2026-12-04 16:59:00 → BUF 2026-12-04 18:30:00.

2026-11-27 → 2026-12-04 · $934.50

  • United Airlines UA5223 / UA970: BUF 2026-11-27 10:42:00 → FCO 2026-11-28 07:45:00; 1 stop(s) via ORD; 903 minutes. Local airport times.
    • UA5223: BUF 2026-11-27 10:42:00 → ORD 2026-11-27 11:59:00; layover at ORD: 221 minutes.
    • UA970: ORD 2026-11-27 15:40:00 → FCO 2026-11-28 07:45:00.
  • United Airlines UA41 / UA3607: FCO 2026-12-04 10:30:00 → BUF 2026-12-04 18:10:00; 1 stop(s) via EWR; 820 minutes. Local airport times.
    • UA41: FCO 2026-12-04 10:30:00 → EWR 2026-12-04 14:10:00; layover at EWR: 150 minutes.
    • UA3607: EWR 2026-12-04 16:40:00 → BUF 2026-12-04 18:10:00.

2026-11-27 → 2026-12-04 · $955.50

  • Delta Air Lines DL5296 / DL230: BUF 2026-11-27 15:20:00 → FCO 2026-11-28 10:45:00; 1 stop(s) via JFK; 805 minutes. Local airport times.
    • DL5296: BUF 2026-11-27 15:20:00 → JFK 2026-11-27 16:53:00; layover at JFK: 212 minutes.
    • DL230: JFK 2026-11-27 20:25:00 → FCO 2026-11-28 10:45:00.
  • Delta Air Lines DL207 / DL3843: FCO 2026-12-04 10:00:00 → BUF 2026-12-04 19:13:00; 1 stop(s) via DTW; 913 minutes. Local airport times.
    • DL207: FCO 2026-12-04 10:00:00 → DTW 2026-12-04 14:30:00; layover at DTW: 206 minutes.
    • DL3843: DTW 2026-12-04 17:56:00 → BUF 2026-12-04 19:13:00.

2026-11-20 → 2026-11-23 · $957.00

  • American Airlines AA5866 / AA718: BUF 2026-11-20 15:41:00 → FCO 2026-11-21 09:00:00; 1 stop(s) via PHL; 679 minutes. Local airport times.
    • AA5866: BUF 2026-11-20 15:41:00 → PHL 2026-11-20 17:17:00; layover at PHL: 83 minutes.
    • AA718: PHL 2026-11-20 18:40:00 → FCO 2026-11-21 09:00:00.
  • American Airlines AA719 / AA5866: FCO 2026-11-23 11:00:00 → BUF 2026-11-23 18:30:00; 1 stop(s) via PHL; 810 minutes. Local airport times.
    • AA719: FCO 2026-11-23 11:00:00 → PHL 2026-11-23 14:40:00; layover at PHL: 139 minutes.
    • AA5866: PHL 2026-11-23 16:59:00 → BUF 2026-11-23 18:30:00.

2026-11-20 · one way · $687.50

  • United Airlines UA4291 / UA884: BUF 2026-11-20 15:00:00 → FCO 2026-11-21 08:30:00; 1 stop(s) via IAD; 690 minutes. Local airport times.
    • UA4291: BUF 2026-11-20 15:00:00 → IAD 2026-11-20 16:25:00; layover at IAD: 75 minutes.
    • UA884: IAD 2026-11-20 17:40:00 → FCO 2026-11-21 08:30:00.

2026-11-20 · one way · $704.00

  • Delta Air Lines DL1384 / DL214: BUF 2026-11-20 12:11:00 → FCO 2026-11-21 08:15:00; 1 stop(s) via ATL; 844 minutes. Local airport times.
    • DL1384: BUF 2026-11-20 12:11:00 → ATL 2026-11-20 14:23:00; layover at ATL: 152 minutes.
    • DL214: ATL 2026-11-20 16:55:00 → FCO 2026-11-21 08:15:00.

2026-11-27 → 2026-12-04 · $934.50

  • United Airlines UA4291 / UA884: BUF 2026-11-27 15:00:00 → FCO 2026-11-28 08:30:00; 1 stop(s) via IAD; 690 minutes. Local airport times.
    • UA4291: BUF 2026-11-27 15:00:00 → IAD 2026-11-27 16:25:00; layover at IAD: 75 minutes.
    • UA884: IAD 2026-11-27 17:40:00 → FCO 2026-11-28 08:30:00.
  • United Airlines UA41 / UA3607: FCO 2026-12-04 10:30:00 → BUF 2026-12-04 18:10:00; 1 stop(s) via EWR; 820 minutes. Local airport times.
    • UA41: FCO 2026-12-04 10:30:00 → EWR 2026-12-04 14:10:00; layover at EWR: 150 minutes.
    • UA3607: EWR 2026-12-04 16:40:00 → BUF 2026-12-04 18:10:00.

2026-11-27 → 2026-12-04 · $955.50

  • Delta Air Lines DL1384 / DL214: BUF 2026-11-27 12:11:00 → FCO 2026-11-28 08:15:00; 1 stop(s) via ATL; 844 minutes. Local airport times.
    • DL1384: BUF 2026-11-27 12:11:00 → ATL 2026-11-27 14:23:00; layover at ATL: 152 minutes.
    • DL214: ATL 2026-11-27 16:55:00 → FCO 2026-11-28 08:15:00.
  • Delta Air Lines DL207 / DL3843: FCO 2026-12-04 10:00:00 → BUF 2026-12-04 19:13:00; 1 stop(s) via DTW; 913 minutes. Local airport times.
    • DL207: FCO 2026-12-04 10:00:00 → DTW 2026-12-04 14:30:00; layover at DTW: 206 minutes.
    • DL3843: DTW 2026-12-04 17:56:00 → BUF 2026-12-04 19:13:00.

2026-11-20 → 2026-11-23 · $979.00

  • United Airlines UA4291 / UA884: BUF 2026-11-20 15:00:00 → FCO 2026-11-21 08:30:00; 1 stop(s) via IAD; 690 minutes. Local airport times.
    • UA4291: BUF 2026-11-20 15:00:00 → IAD 2026-11-20 16:25:00; layover at IAD: 75 minutes.
    • UA884: IAD 2026-11-20 17:40:00 → FCO 2026-11-21 08:30:00.
  • United Airlines UA41 / UA3607: FCO 2026-11-23 10:30:00 → BUF 2026-11-23 18:10:00; 1 stop(s) via EWR; 820 minutes. Local airport times.
    • UA41: FCO 2026-11-23 10:30:00 → EWR 2026-11-23 14:10:00; layover at EWR: 150 minutes.
    • UA3607: EWR 2026-11-23 16:40:00 → BUF 2026-11-23 18:10:00.

2026-11-20 → 2026-11-23 · $979.00

  • United Airlines UA5223 / UA970: BUF 2026-11-20 10:42:00 → FCO 2026-11-21 07:45:00; 1 stop(s) via ORD; 903 minutes. Local airport times.
    • UA5223: BUF 2026-11-20 10:42:00 → ORD 2026-11-20 11:59:00; layover at ORD: 221 minutes.
    • UA970: ORD 2026-11-20 15:40:00 → FCO 2026-11-21 07:45:00.
  • United Airlines UA41 / UA3607: FCO 2026-11-23 10:30:00 → BUF 2026-11-23 18:10:00; 1 stop(s) via EWR; 820 minutes. Local airport times.
    • UA41: FCO 2026-11-23 10:30:00 → EWR 2026-11-23 14:10:00; layover at EWR: 150 minutes.
    • UA3607: EWR 2026-11-23 16:40:00 → BUF 2026-11-23 18:10:00.

2026-11-20 → 2026-11-23 · $1001.00

  • Delta Air Lines DL1384 / DL214: BUF 2026-11-20 12:11:00 → FCO 2026-11-21 08:15:00; 1 stop(s) via ATL; 844 minutes. Local airport times.
    • DL1384: BUF 2026-11-20 12:11:00 → ATL 2026-11-20 14:23:00; layover at ATL: 152 minutes.
    • DL214: ATL 2026-11-20 16:55:00 → FCO 2026-11-21 08:15:00.
  • Delta Air Lines DL207 / DL3843: FCO 2026-11-23 10:00:00 → BUF 2026-11-23 19:13:00; 1 stop(s) via DTW; 913 minutes. Local airport times.
    • DL207: FCO 2026-11-23 10:00:00 → DTW 2026-11-23 14:30:00; layover at DTW: 206 minutes.
    • DL3843: DTW 2026-11-23 17:56:00 → BUF 2026-11-23 19:13:00.

2026-11-20 → 2026-11-23 · $1001.00

  • Delta Air Lines DL5296 / DL230: BUF 2026-11-20 15:20:00 → FCO 2026-11-21 10:45:00; 1 stop(s) via JFK; 805 minutes. Local airport times.
    • DL5296: BUF 2026-11-20 15:20:00 → JFK 2026-11-20 16:53:00; layover at JFK: 212 minutes.
    • DL230: JFK 2026-11-20 20:25:00 → FCO 2026-11-21 10:45:00.
  • Delta Air Lines DL207 / DL3843: FCO 2026-11-23 10:00:00 → BUF 2026-11-23 19:13:00; 1 stop(s) via DTW; 913 minutes. Local airport times.
    • DL207: FCO 2026-11-23 10:00:00 → DTW 2026-11-23 14:30:00; layover at DTW: 206 minutes.
    • DL3843: DTW 2026-11-23 17:56:00 → BUF 2026-11-23 19:13:00.

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