Boston (BOS) to Saint Louis (STL) · Nov 22, 2026 · return Dec 6, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in St. Louis for these nights (Nov 22 – Dec 6, 2026 · 14 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $951 total · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton, $1,880 total · 5★ Four Seasons Hotel St Louis, $5,290 total

All hotels in St. Louis

Route overview: Boston to Saint Louis (STL) flight deals

2026-11-22 → 2026-12-06 · Axel-exclusive $280.00

• Southwest Airlines WN4929: BOS 2026-11-22 18:50:00 → STL 2026-11-22 21:00:00; nonstop; 190 minutes. Local airport times.
• Southwest Airlines WN4431: STL 2026-12-06 20:50:00 → BOS 2026-12-07 00:15:00; nonstop; 145 minutes. Local airport times.

2026-11-22 → 2026-12-06 · Axel-exclusive $290.00

• American Airlines AA3788: BOS 2026-11-22 07:00:00 → STL 2026-11-22 09:28:00; nonstop; 208 minutes. Local airport times.
• American Airlines AA4801: STL 2026-12-06 13:15:00 → BOS 2026-12-06 16:55:00; nonstop; 160 minutes. Local airport times.

2026-11-22 → 2026-12-06 · Axel-exclusive $230.00

• Frontier Airlines F93511 / F94473: BOS 2026-11-22 12:15:00 → STL 2026-11-22 17:42:00; 1 stop(s) via ATL; 387 minutes. Local airport times.
  • F93511: BOS 2026-11-22 12:15:00 → ATL 2026-11-22 15:36:00; layover at ATL: 73 minutes.
  • F94473: ATL 2026-11-22 16:49:00 → STL 2026-11-22 17:42:00.
• Southwest Airlines WN4431: STL 2026-12-06 20:50:00 → BOS 2026-12-07 00:15:00; nonstop; 145 minutes. Local airport times.

2026-11-22 → 2026-12-06 · Axel-exclusive $270.00

• United Airlines UA1734 / UA4427: BOS 2026-11-22 05:45:00 → STL 2026-11-22 10:12:00; 1 stop(s) via IAD; 327 minutes. Local airport times.
  • UA1734: BOS 2026-11-22 05:45:00 → IAD 2026-11-22 07:25:00; layover at IAD: 75 minutes.
  • UA4427: IAD 2026-11-22 08:40:00 → STL 2026-11-22 10:12:00.
• United Airlines UA1344 / UA1669: STL 2026-12-06 06:00:00 → BOS 2026-12-06 12:27:00; 1 stop(s) via EWR; 327 minutes. Local airport times.
  • UA1344: STL 2026-12-06 06:00:00 → EWR 2026-12-06 09:21:00; layover at EWR: 115 minutes.
  • UA1669: EWR 2026-12-06 11:16:00 → BOS 2026-12-06 12:27:00.

2026-11-22 → 2026-12-06 · Axel-exclusive $280.00

• Delta Air Lines DL2222 / DL2822: BOS 2026-11-22 13:04:00 → STL 2026-11-22 17:20:00; 1 stop(s) via DTW; 316 minutes. Local airport times.
  • DL2222: BOS 2026-11-22 13:04:00 → DTW 2026-11-22 15:19:00; layover at DTW: 74 minutes.
  • DL2822: DTW 2026-11-22 16:33:00 → STL 2026-11-22 17:20:00.
• Delta Air Lines DL2868 / DL1171: STL 2026-12-06 10:14:00 → BOS 2026-12-06 16:04:00; 1 stop(s) via DTW; 290 minutes. Local airport times.
  • DL2868: STL 2026-12-06 10:14:00 → DTW 2026-12-06 12:46:00; layover at DTW: 81 minutes.
  • DL1171: DTW 2026-12-06 14:07:00 → BOS 2026-12-06 16:04:00.

2026-11-22 → 2026-12-06 · Axel-exclusive $280.00

• Southwest Airlines WN819: BOS 2026-11-22 05:10:00 → STL 2026-11-22 07:15:00; nonstop; 185 minutes. Local airport times.
• Southwest Airlines WN4431: STL 2026-12-06 20:50:00 → BOS 2026-12-07 00:15:00; nonstop; 145 minutes. Local airport times.

2026-11-22 → 2026-12-06 · Axel-exclusive $290.00

• American Airlines AA4678: BOS 2026-11-22 15:25:00 → STL 2026-11-22 17:47:00; nonstop; 202 minutes. Local airport times.
• American Airlines AA4801: STL 2026-12-06 13:15:00 → BOS 2026-12-06 16:55:00; nonstop; 160 minutes. Local airport times.

2026-11-22 → 2026-12-06 · Axel-exclusive $270.00

• Southwest Airlines WN1888 / WN2730: BOS 2026-11-22 13:20:00 → STL 2026-11-22 18:05:00; 1 stop(s) via BWI; 345 minutes. Local airport times.
  • WN1888: BOS 2026-11-22 13:20:00 → BWI 2026-11-22 14:55:00; layover at BWI: 110 minutes.
  • WN2730: BWI 2026-11-22 16:45:00 → STL 2026-11-22 18:05:00.
• Southwest Airlines WN4431: STL 2026-12-06 20:50:00 → BOS 2026-12-07 00:15:00; nonstop; 145 minutes. Local airport times.

2026-11-22 → 2026-12-06 · Axel-exclusive $275.00

• American Airlines AA1198 / AA5224: BOS 2026-11-22 16:00:00 → STL 2026-11-22 20:31:00; 1 stop(s) via PHL; 331 minutes. Local airport times.
  • AA1198: BOS 2026-11-22 16:00:00 → PHL 2026-11-22 17:40:00; layover at PHL: 60 minutes.
  • AA5224: PHL 2026-11-22 18:40:00 → STL 2026-11-22 20:31:00.
• American Airlines AA4801: STL 2026-12-06 13:15:00 → BOS 2026-12-06 16:55:00; nonstop; 160 minutes. Local airport times.

2026-11-22 → 2026-12-06 · Axel-exclusive $275.00

• American Airlines AA1249 / AA2486: BOS 2026-11-22 05:00:00 → STL 2026-11-22 10:19:00; 1 stop(s) via CLT; 379 minutes. Local airport times.
  • AA1249: BOS 2026-11-22 05:00:00 → CLT 2026-11-22 07:34:00; layover at CLT: 101 minutes.
  • AA2486: CLT 2026-11-22 09:15:00 → STL 2026-11-22 10:19:00.
• American Airlines AA4801: STL 2026-12-06 13:15:00 → BOS 2026-12-06 16:55:00; nonstop; 160 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 21, 2026 · Return options
• Nov 23, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Boston (BOS) to Saint Louis (STL) · Nov 22, 2026 · return Dec 6, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
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