Boston (BOS) to Saint Louis (STL), Nov 20–26, 2026: from $286 round trip

Boston (BOS) to Saint Louis (STL), Nov 20–26, 2026: from $286 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $286 round trip, Axel-exclusive, Frontier Airlines / Southwest Airlines, 1 stop, Nov 20–26, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in St. Louis for these nights (Nov 20–26, 2026 · 6 nights · 2 adults, 1 room): 3★ Hampton Inn & Suites St. Louis at Forest Park · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis

All hotels in St. Louis

Route overview: Boston to Saint Louis (STL) flight deals

2026-11-20 → 2026-11-26 · Axel-exclusive $336.00

• Southwest Airlines WN4929: BOS 2026-11-20 17:05:00 → STL 2026-11-20 19:15:00; nonstop; 190 minutes. Local airport times.
• Southwest Airlines WN4431: STL 2026-11-26 18:10:00 → BOS 2026-11-26 21:45:00; nonstop; 155 minutes. Local airport times.

2026-11-20 → 2026-11-26 · Axel-exclusive $348.00

• American Airlines AA3444: BOS 2026-11-20 07:00:00 → STL 2026-11-20 09:26:00; nonstop; 206 minutes. Local airport times.
• American Airlines AA3444: STL 2026-11-26 09:59:00 → BOS 2026-11-26 13:36:00; nonstop; 157 minutes. Local airport times.

2026-11-20 → 2026-11-26 · Axel-exclusive $286.00

• Frontier Airlines F93511 / F94473: BOS 2026-11-20 12:15:00 → STL 2026-11-20 17:42:00; 1 stop(s) via ATL; 387 minutes. Local airport times.
  • F93511: BOS 2026-11-20 12:15:00 → ATL 2026-11-20 15:36:00; layover at ATL: 73 minutes.
  • F94473: ATL 2026-11-20 16:49:00 → STL 2026-11-20 17:42:00.
• Southwest Airlines WN4431: STL 2026-11-26 18:10:00 → BOS 2026-11-26 21:45:00; nonstop; 155 minutes. Local airport times.

2026-11-20 → 2026-11-26 · Axel-exclusive $324.00

• United Airlines UA1734 / UA4427: BOS 2026-11-20 05:45:00 → STL 2026-11-20 10:12:00; 1 stop(s) via IAD; 327 minutes. Local airport times.
  • UA1734: BOS 2026-11-20 05:45:00 → IAD 2026-11-20 07:25:00; layover at IAD: 75 minutes.
  • UA4427: IAD 2026-11-20 08:40:00 → STL 2026-11-20 10:12:00.
• United Airlines UA1344 / UA1669: STL 2026-11-26 06:00:00 → BOS 2026-11-26 12:27:00; 1 stop(s) via EWR; 327 minutes. Local airport times.
  • UA1344: STL 2026-11-26 06:00:00 → EWR 2026-11-26 09:21:00; layover at EWR: 115 minutes.
  • UA1669: EWR 2026-11-26 11:16:00 → BOS 2026-11-26 12:27:00.

2026-11-20 → 2026-11-26 · Axel-exclusive $336.00

• Delta Air Lines DL2222 / DL2822: BOS 2026-11-20 13:04:00 → STL 2026-11-20 17:20:00; 1 stop(s) via DTW; 316 minutes. Local airport times.
  • DL2222: BOS 2026-11-20 13:04:00 → DTW 2026-11-20 15:19:00; layover at DTW: 74 minutes.
  • DL2822: DTW 2026-11-20 16:33:00 → STL 2026-11-20 17:20:00.
• Delta Air Lines DL2868 / DL1171: STL 2026-11-26 10:14:00 → BOS 2026-11-26 16:04:00; 1 stop(s) via DTW; 290 minutes. Local airport times.
  • DL2868: STL 2026-11-26 10:14:00 → DTW 2026-11-26 12:46:00; layover at DTW: 81 minutes.
  • DL1171: DTW 2026-11-26 14:07:00 → BOS 2026-11-26 16:04:00.

2026-11-20 → 2026-11-26 · Axel-exclusive $336.00

• Southwest Airlines WN819: BOS 2026-11-20 05:20:00 → STL 2026-11-20 07:30:00; nonstop; 190 minutes. Local airport times.
• Southwest Airlines WN4431: STL 2026-11-26 18:10:00 → BOS 2026-11-26 21:45:00; nonstop; 155 minutes. Local airport times.

2026-11-20 → 2026-11-26 · Axel-exclusive $348.00

• American Airlines AA4500: BOS 2026-11-20 16:14:00 → STL 2026-11-20 18:40:00; nonstop; 206 minutes. Local airport times.
• American Airlines AA3444: STL 2026-11-26 09:59:00 → BOS 2026-11-26 13:36:00; nonstop; 157 minutes. Local airport times.

2026-11-20 → 2026-11-26 · Axel-exclusive $326.00

• Southwest Airlines WN1888 / WN2730: BOS 2026-11-20 13:20:00 → STL 2026-11-20 18:05:00; 1 stop(s) via BWI; 345 minutes. Local airport times.
  • WN1888: BOS 2026-11-20 13:20:00 → BWI 2026-11-20 14:55:00; layover at BWI: 110 minutes.
  • WN2730: BWI 2026-11-20 16:45:00 → STL 2026-11-20 18:05:00.
• Southwest Airlines WN4431: STL 2026-11-26 18:10:00 → BOS 2026-11-26 21:45:00; nonstop; 155 minutes. Local airport times.

2026-11-20 → 2026-11-26 · Axel-exclusive $333.00

• American Airlines AA1198 / AA5224: BOS 2026-11-20 16:00:00 → STL 2026-11-20 20:31:00; 1 stop(s) via PHL; 331 minutes. Local airport times.
  • AA1198: BOS 2026-11-20 16:00:00 → PHL 2026-11-20 17:40:00; layover at PHL: 60 minutes.
  • AA5224: PHL 2026-11-20 18:40:00 → STL 2026-11-20 20:31:00.
• American Airlines AA3444: STL 2026-11-26 09:59:00 → BOS 2026-11-26 13:36:00; nonstop; 157 minutes. Local airport times.

2026-11-20 → 2026-11-26 · Axel-exclusive $333.00

• American Airlines AA1249 / AA2486: BOS 2026-11-20 05:00:00 → STL 2026-11-20 10:19:00; 1 stop(s) via CLT; 379 minutes. Local airport times.
  • AA1249: BOS 2026-11-20 05:00:00 → CLT 2026-11-20 07:34:00; layover at CLT: 101 minutes.
  • AA2486: CLT 2026-11-20 09:15:00 → STL 2026-11-20 10:19:00.
• American Airlines AA3444: STL 2026-11-26 09:59:00 → BOS 2026-11-26 13:36:00; nonstop; 157 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 19, 2026 · Return options
• Nov 21, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Boston (BOS) to Saint Louis (STL) · Nov 20, 2026 · return Nov 26, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Boston to Saint Louis (STL) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

Feedback (optional): Missing info · Axel issue