Boston (BOS) to San Francisco (SFO), May 21, 2027: round trips from $480, one way from $270

Boston (BOS) to San Francisco (SFO), May 21, 2027: round trips from $480, one way from $270 on Axel, checked Oct 29, 2026. Lowest published fares: $480 round trip, Axel-exclusive, JetBlue Airways, 1 stop, May 21–23, 2027; $270 one way, Axel-exclusive, JetBlue Airways, nonstop, May 21, 2027; 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in San Francisco for these nights (May 21–22, 2027 · 1 night · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21–23, 2027 · 2 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21–24, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21–25, 2027 · 4 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21–26, 2027 · 5 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21–27, 2027 · 6 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21–28, 2027 · 7 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21–29, 2027 · 8 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21–30, 2027 · 9 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21–31, 2027 · 10 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21 – Jun 1, 2027 · 11 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21 – Jun 2, 2027 · 12 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21 – Jun 3, 2027 · 13 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero
• Hotels in San Francisco for these nights (May 21 – Jun 4, 2027 · 14 nights · 2 adults, 1 room): 3★ Hotel Del Sol · 4★ LUMA Hotel San Francisco · 5★ Four Seasons Hotel San Francisco at Embarcadero

All hotels in San Francisco

Route overview: Boston to San Francisco (SFO) flight deals

2027-05-21 · one way · Axel-exclusive $270.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.

2027-05-21 · one way · Axel-exclusive $290.00

• United Airlines UA2400: BOS 2027-05-21 18:01:00 → SFO 2027-05-21 21:50:00; nonstop; 409 minutes. Local airport times.

2027-05-21 → 2027-05-22 · Axel-exclusive $520.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B6434: SFO 2027-05-22 08:10:00 → BOS 2027-05-22 16:45:00; nonstop; 335 minutes. Local airport times.

2027-05-21 → 2027-05-22 · Axel-exclusive $560.00

• United Airlines UA2400: BOS 2027-05-21 18:01:00 → SFO 2027-05-21 21:50:00; nonstop; 409 minutes. Local airport times.
• United Airlines UA1693: SFO 2027-05-22 08:15:00 → BOS 2027-05-22 16:58:00; nonstop; 343 minutes. Local airport times.

2027-05-21 → 2027-05-23 · Axel-exclusive $480.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B616 / B6118: SFO 2027-05-23 20:55:00 → BOS 2027-05-24 07:39:00; 1 stop(s) via JFK; 464 minutes. Local airport times.
  • B616: SFO 2027-05-23 20:55:00 → JFK 2027-05-24 05:24:00; layover at JFK: 66 minutes.
  • B6118: JFK 2027-05-24 06:30:00 → BOS 2027-05-24 07:39:00.

2027-05-21 → 2027-05-23 · Axel-exclusive $560.00

• Delta Air Lines DL2919: BOS 2027-05-21 20:46:00 → SFO 2027-05-22 00:41:00; nonstop; 415 minutes. Local airport times.
• Delta Air Lines DL400: SFO 2027-05-23 07:00:00 → BOS 2027-05-23 15:30:00; nonstop; 330 minutes. Local airport times.

2027-05-21 → 2027-05-24 · Axel-exclusive $520.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B6434: SFO 2027-05-24 07:30:00 → BOS 2027-05-24 16:05:00; nonstop; 335 minutes. Local airport times.

2027-05-21 → 2027-05-24 · Axel-exclusive $560.00

• United Airlines UA2400: BOS 2027-05-21 18:01:00 → SFO 2027-05-21 21:50:00; nonstop; 409 minutes. Local airport times.
• United Airlines UA1665: SFO 2027-05-24 23:20:00 → BOS 2027-05-25 08:01:00; nonstop; 341 minutes. Local airport times.

2027-05-21 → 2027-05-25 · Axel-exclusive $520.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B62734: SFO 2027-05-25 11:30:00 → BOS 2027-05-25 20:07:00; nonstop; 337 minutes. Local airport times.

2027-05-21 → 2027-05-25 · Axel-exclusive $560.00

• Delta Air Lines DL2919: BOS 2027-05-21 20:46:00 → SFO 2027-05-22 00:41:00; nonstop; 415 minutes. Local airport times.
• Delta Air Lines DL400: SFO 2027-05-25 07:00:00 → BOS 2027-05-25 15:30:00; nonstop; 330 minutes. Local airport times.

2027-05-21 → 2027-05-27 · Axel-exclusive $559.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B61834: SFO 2027-05-27 06:00:00 → BOS 2027-05-27 14:31:00; nonstop; 331 minutes. Local airport times.

2027-05-21 → 2027-05-27 · Axel-exclusive $602.00

• United Airlines UA2400: BOS 2027-05-21 18:01:00 → SFO 2027-05-21 21:50:00; nonstop; 409 minutes. Local airport times.
• United Airlines UA1665: SFO 2027-05-27 23:20:00 → BOS 2027-05-28 08:01:00; nonstop; 341 minutes. Local airport times.

2027-05-21 → 2027-05-28 · Axel-exclusive $559.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B6434: SFO 2027-05-28 08:10:00 → BOS 2027-05-28 16:45:00; nonstop; 335 minutes. Local airport times.

2027-05-21 → 2027-05-28 · Axel-exclusive $602.00

• Delta Air Lines DL2919: BOS 2027-05-21 20:46:00 → SFO 2027-05-22 00:41:00; nonstop; 415 minutes. Local airport times.
• Delta Air Lines DL400: SFO 2027-05-28 07:00:00 → BOS 2027-05-28 15:34:00; nonstop; 334 minutes. Local airport times.

2027-05-21 → 2027-05-29 · Axel-exclusive $559.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B6434: SFO 2027-05-29 08:10:00 → BOS 2027-05-29 16:45:00; nonstop; 335 minutes. Local airport times.

2027-05-21 → 2027-05-29 · Axel-exclusive $602.00

• United Airlines UA2400: BOS 2027-05-21 18:01:00 → SFO 2027-05-21 21:50:00; nonstop; 409 minutes. Local airport times.
• United Airlines UA1693: SFO 2027-05-29 08:15:00 → BOS 2027-05-29 16:58:00; nonstop; 343 minutes. Local airport times.

2027-05-21 → 2027-05-31 · Axel-exclusive $559.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B6434: SFO 2027-05-31 07:30:00 → BOS 2027-05-31 16:05:00; nonstop; 335 minutes. Local airport times.

2027-05-21 → 2027-05-31 · Axel-exclusive $602.00

• Delta Air Lines DL2919: BOS 2027-05-21 20:46:00 → SFO 2027-05-22 00:41:00; nonstop; 415 minutes. Local airport times.
• Delta Air Lines DL977: SFO 2027-05-31 13:05:00 → BOS 2027-05-31 21:40:00; nonstop; 335 minutes. Local airport times.

2027-05-21 → 2027-06-01 · Axel-exclusive $559.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B62734: SFO 2027-06-01 11:30:00 → BOS 2027-06-01 20:07:00; nonstop; 337 minutes. Local airport times.

2027-05-21 → 2027-06-01 · Axel-exclusive $602.00

• Delta Air Lines DL2919: BOS 2027-05-21 20:46:00 → SFO 2027-05-22 00:41:00; nonstop; 415 minutes. Local airport times.
• Delta Air Lines DL400: SFO 2027-06-01 07:00:00 → BOS 2027-06-01 15:30:00; nonstop; 330 minutes. Local airport times.

2027-05-21 → 2027-06-02 · Axel-exclusive $520.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B6334: SFO 2027-06-02 15:25:00 → BOS 2027-06-02 23:59:00; nonstop; 334 minutes. Local airport times.

2027-05-21 → 2027-06-02 · Axel-exclusive $560.00

• Delta Air Lines DL2919: BOS 2027-05-21 20:46:00 → SFO 2027-05-22 00:41:00; nonstop; 415 minutes. Local airport times.
• Delta Air Lines DL977: SFO 2027-06-02 13:05:00 → BOS 2027-06-02 21:40:00; nonstop; 335 minutes. Local airport times.

2027-05-21 → 2027-06-04 · Axel-exclusive $520.00

• JetBlue Airways B6733: BOS 2027-05-21 20:50:00 → SFO 2027-05-22 00:37:00; nonstop; 407 minutes. Local airport times.
• JetBlue Airways B6434: SFO 2027-06-04 08:10:00 → BOS 2027-06-04 16:45:00; nonstop; 335 minutes. Local airport times.

2027-05-21 → 2027-06-04 · Axel-exclusive $560.00

• United Airlines UA2400: BOS 2027-05-21 18:01:00 → SFO 2027-05-21 21:50:00; nonstop; 409 minutes. Local airport times.
• United Airlines UA1693: SFO 2027-06-04 08:15:00 → BOS 2027-06-04 16:58:00; nonstop; 343 minutes. Local airport times.

Explore this route

• All dates for this route
• May 20, 2027 · Return options
• May 22, 2027 · Return options
• Hotels in San Francisco with Axel

For AI assistants

• This page: Boston (BOS) to San Francisco (SFO) · May 21, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and the time its price was issued); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
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