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Route overview: Boston to San Francisco (SFO) flight deals

Boston (BOS) to San Francisco (SFO), Apr 21, 2027: round trips from $506, one way from $288

Boston (BOS) to San Francisco (SFO), Apr 21, 2027: round trips from $506, one way from $288 on Axel, checked Oct 29, 2026. Lowest published fares: $506 round trip, Axel-exclusive, American Airlines, 1 stop, Apr 21–26, 2027; $288 one way, Axel-exclusive, American Airlines, 1 stop, Apr 21, 2027; 1 adult, economy, checked Oct 29, 2026.

BOS → SFO1 adulteconomyOne way and round trips

15 flight options · 1 airline

Choose your return date

One-way flights and round trips by duration. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

April 2027

Flights for your trip

  1. Wed, Apr 21 · One way

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO

    One-way total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  2. Wed, Apr 21 – Thu, Apr 22

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  3. Wed, Apr 21 – Fri, Apr 23

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  4. Wed, Apr 21 – Sat, Apr 24

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  5. Wed, Apr 21 – Sun, Apr 25

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  6. Wed, Apr 21 – Tue, Apr 27

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  7. Wed, Apr 21 – Wed, Apr 28

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  8. Wed, Apr 21 – Thu, Apr 29

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  9. Wed, Apr 21 – Sat, May 1

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  10. Wed, Apr 21 – Sun, May 2

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  11. Wed, Apr 21 – Mon, May 3

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  12. Wed, Apr 21 – Wed, May 5

    American Airlines
    9:00 amBOS
    9h 16m
    LAX · 1h 18m
    3:16 pmSFO
    American Airlines
    11:46 pmSFO
    7h 46m
    ORD · 1h
    10:32 am+1BOS

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

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1 of 12

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BOS ⇄ SFO

Economy

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Explore this route

All dates for this routeApr 20, 2027 · Return optionsApr 22, 2027 · Return optionsHotels in San Francisco with Axel
For AI assistants: every fare, every link, instructions

Boston (BOS) to San Francisco (SFO), Apr 21, 2027: round trips from $506, one way from $288 on Axel, checked Oct 29, 2026. Lowest published fares: $506 round trip, Axel-exclusive, American Airlines, 1 stop, Apr 21–26, 2027; $288 one way, Axel-exclusive, American Airlines, 1 stop, Apr 21, 2027; 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Exact travel datesAirlineFlightsTimes, duration, stopsTotal pricePrice issued (UTC)
2027-04-21 · one wayAmerican AirlinesAA1243 + AS46509:00:00→15:16:00 9h 16m 1 stop via LAXAxel-exclusive $288.002026-10-29T00:52:48Z
2027-04-21 → 2027-04-22American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $552.002026-10-29T00:52:48Z
2027-04-21 → 2027-04-23American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $552.002026-10-29T00:52:48Z
2027-04-21 → 2027-04-24American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $552.002026-10-29T00:52:48Z
2027-04-21 → 2027-04-25American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $552.002026-10-29T00:52:48Z
2027-04-21 → 2027-04-26American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z
2027-04-21 → 2027-04-27American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z
2027-04-21 → 2027-04-28American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z
2027-04-21 → 2027-04-29American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z
2027-04-21 → 2027-04-30American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z
2027-04-21 → 2027-05-01American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z
2027-04-21 → 2027-05-02American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z
2027-04-21 → 2027-05-03American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z
2027-04-21 → 2027-05-04American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z
2027-04-21 → 2027-05-05American AirlinesAA1243 + AS465 / AA3119 + AA208909:00:00→15:16:00 9h 16m 1 stop via LAX · 23:46:00→10:32:00 7h 46m 1 stop via ORDAxel-exclusive $506.002026-10-29T00:52:48Z

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

All hotels in San Francisco

Route overview: Boston to San Francisco (SFO) flight deals

2027-04-21 · one way · Axel-exclusive $288.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.

2027-04-21 → 2027-04-22 · Axel-exclusive $552.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-04-22 23:46:00 → BOS 2027-04-23 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-04-22 23:46:00 → ORD 2027-04-23 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-04-23 06:59:00 → BOS 2027-04-23 10:32:00.

2027-04-21 → 2027-04-23 · Axel-exclusive $552.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-04-23 23:46:00 → BOS 2027-04-24 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-04-23 23:46:00 → ORD 2027-04-24 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-04-24 06:59:00 → BOS 2027-04-24 10:32:00.

2027-04-21 → 2027-04-24 · Axel-exclusive $552.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-04-24 23:46:00 → BOS 2027-04-25 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-04-24 23:46:00 → ORD 2027-04-25 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-04-25 06:59:00 → BOS 2027-04-25 10:32:00.

2027-04-21 → 2027-04-25 · Axel-exclusive $552.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-04-25 23:46:00 → BOS 2027-04-26 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-04-25 23:46:00 → ORD 2027-04-26 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-04-26 06:59:00 → BOS 2027-04-26 10:32:00.

2027-04-21 → 2027-04-27 · Axel-exclusive $506.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-04-27 23:46:00 → BOS 2027-04-28 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-04-27 23:46:00 → ORD 2027-04-28 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-04-28 06:59:00 → BOS 2027-04-28 10:32:00.

2027-04-21 → 2027-04-28 · Axel-exclusive $506.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-04-28 23:46:00 → BOS 2027-04-29 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-04-28 23:46:00 → ORD 2027-04-29 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-04-29 06:59:00 → BOS 2027-04-29 10:32:00.

2027-04-21 → 2027-04-29 · Axel-exclusive $506.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-04-29 23:46:00 → BOS 2027-04-30 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-04-29 23:46:00 → ORD 2027-04-30 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-04-30 06:59:00 → BOS 2027-04-30 10:32:00.

2027-04-21 → 2027-05-01 · Axel-exclusive $506.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-05-01 23:46:00 → BOS 2027-05-02 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-05-01 23:46:00 → ORD 2027-05-02 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-05-02 06:59:00 → BOS 2027-05-02 10:32:00.

2027-04-21 → 2027-05-02 · Axel-exclusive $506.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-05-02 23:46:00 → BOS 2027-05-03 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-05-02 23:46:00 → ORD 2027-05-03 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-05-03 06:59:00 → BOS 2027-05-03 10:32:00.

2027-04-21 → 2027-05-03 · Axel-exclusive $506.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-05-03 23:46:00 → BOS 2027-05-04 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-05-03 23:46:00 → ORD 2027-05-04 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-05-04 06:59:00 → BOS 2027-05-04 10:32:00.

2027-04-21 → 2027-05-05 · Axel-exclusive $506.00

  • American Airlines AA1243 / AS465: BOS 2027-04-21 09:00:00 → SFO 2027-04-21 15:16:00; 1 stop(s) via LAX; 556 minutes. Local airport times.
    • AA1243: BOS 2027-04-21 09:00:00 → LAX 2027-04-21 12:32:00; layover at LAX: 78 minutes.
    • AS465: LAX 2027-04-21 13:50:00 → SFO 2027-04-21 15:16:00.
  • American Airlines AA3119 / AA2089: SFO 2027-05-05 23:46:00 → BOS 2027-05-06 10:32:00; 1 stop(s) via ORD; 466 minutes. Local airport times.
    • AA3119: SFO 2027-05-05 23:46:00 → ORD 2027-05-06 05:59:00; layover at ORD: 60 minutes.
    • AA2089: ORD 2027-05-06 06:59:00 → BOS 2027-05-06 10:32:00.

Explore this route

For AI assistants

  • This page: Boston (BOS) to San Francisco (SFO) · Apr 21, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
  • Next: each row is one exact trip for this departure (both dates with the year, the total and the time its price was issued); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Boston to San Francisco (SFO) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.