Boston (BOS) to San Francisco (SFO), Apr 21, 2027: round trips from $479, one way from $243

Boston (BOS) to San Francisco (SFO), Apr 21, 2027: round trips from $479, one way from $243 on Axel, checked Nov 12, 2026. Lowest published fares: $479 round trip, Axel-exclusive, JetBlue Airways, nonstop, Apr 21–22, 2027; $243 one way, Axel-exclusive, JetBlue Airways, nonstop, Apr 21, 2027; 1 adult, economy, checked Nov 12, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in San Francisco for these nights (Apr 21–22, 2027 · 1 night · 2 adults, 1 room): 3★ Holiday Inn Golden Gateway by IHG, $187 a night · 4★ Stanford Court San Francisco, $233 a night · 5★ Taj Campton Place, $341 a night
• Hotels in San Francisco for these nights (Apr 21–23, 2027 · 2 nights · 2 adults, 1 room): 3★ Hotel Garrett, $173 a night, $345 for 2 nights · 4★ Stanford Court San Francisco, $200 a night, $400 for 2 nights · 5★ Taj Campton Place, $374 a night, $748 for 2 nights
• Hotels in San Francisco for these nights (Apr 21–24, 2027 · 3 nights · 2 adults, 1 room): 3★ Tilden Hotel, $164 a night, $492 for 3 nights · 4★ Stanford Court San Francisco, $190 a night, $569 for 3 nights · 5★ Taj Campton Place, $363 a night, $1,089 for 3 nights
• Hotels in San Francisco for these nights (Apr 21–25, 2027 · 4 nights · 2 adults, 1 room): 3★ Tilden Hotel, $153 a night, $611 for 4 nights · 4★ Stanford Court San Francisco, $184 a night, $736 for 4 nights · 5★ Neighbourgood Sutter Mansion, $350 a night, $1,398 for 4 nights
• Hotels in San Francisco for these nights (Apr 21–26, 2027 · 5 nights · 2 adults, 1 room): 3★ Tilden Hotel, $146 a night, $731 for 5 nights · 4★ Stanford Court San Francisco, $180 a night, $901 for 5 nights · 5★ Neighbourgood Sutter Mansion, $343 a night, $1,713 for 5 nights
• Hotels in San Francisco for these nights (Apr 21–27, 2027 · 6 nights · 2 adults, 1 room): 3★ Tilden Hotel, $143 a night, $858 for 6 nights · 4★ Stanford Court San Francisco, $179 a night, $1,072 for 6 nights · 5★ Taj Campton Place, $343 a night, $2,060 for 6 nights
• Hotels in San Francisco for these nights (Apr 21–28, 2027 · 7 nights · 2 adults, 1 room): 3★ Tilden Hotel, $140 a night, $980 for 7 nights · 4★ Stanford Court San Francisco, $177 a night, $1,237 for 7 nights · 5★ Taj Campton Place, $343 a night, $2,401 for 7 nights
• Hotels in San Francisco for these nights (Apr 21–29, 2027 · 8 nights · 2 adults, 1 room): 3★ Tilden Hotel, $140 a night, $1,122 for 8 nights · 4★ Stanford Court San Francisco, $175 a night, $1,402 for 8 nights · 5★ Taj Campton Place, $343 a night, $2,742 for 8 nights
• Hotels in San Francisco for these nights (Apr 21–30, 2027 · 9 nights · 2 adults, 1 room): 3★ Tilden Hotel, $141 a night, $1,266 for 9 nights · 4★ Stanford Court San Francisco, $174 a night, $1,567 for 9 nights · 5★ Taj Campton Place, $343 a night, $3,083 for 9 nights
• Hotels in San Francisco for these nights (Apr 21 – May 1, 2027 · 10 nights · 2 adults, 1 room): 3★ Tilden Hotel, $139 a night, $1,390 for 10 nights · 4★ Stanford Court San Francisco, $173 a night, $1,732 for 10 nights · 5★ Taj Campton Place, $342 a night, $3,424 for 10 nights
• Hotels in San Francisco for these nights (Apr 21 – May 2, 2027 · 11 nights · 2 adults, 1 room): 3★ Tilden Hotel, $138 a night, $1,519 for 11 nights · 4★ Hotel Bijou - Union Square, $174 a night, $1,911 for 11 nights · 5★ Taj Campton Place, $348 a night, $3,829 for 11 nights
• Hotels in San Francisco for these nights (Apr 21 – May 3, 2027 · 12 nights · 2 adults, 1 room): 3★ Tilden Hotel, $138 a night, $1,651 for 12 nights · 4★ Hotel Bijou - Union Square, $171 a night, $2,054 for 12 nights · 5★ Taj Campton Place, $348 a night, $4,170 for 12 nights
• Hotels in San Francisco for these nights (Apr 21 – May 4, 2027 · 13 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $138 a night, $1,790 for 13 nights · 4★ Stanford Court San Francisco, $177 a night, $2,301 for 13 nights · 5★ Taj Campton Place, $347 a night, $4,511 for 13 nights
• Hotels in San Francisco for these nights (Apr 21 – May 5, 2027 · 14 nights · 2 adults, 1 room): 3★ The Pickwick Hotel, $145 a night, $2,027 for 14 nights · 4★ Stanford Court San Francisco, $181 a night, $2,538 for 14 nights · 5★ Taj Campton Place, $352 a night, $4,926 for 14 nights

All hotels in San Francisco

Route overview: Boston to San Francisco (SFO) flight deals

2027-04-21 · one way · Axel-exclusive $243

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.

2027-04-21 · one way · Axel-exclusive $243

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.

2027-04-21 → 2027-04-22 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B6734: SFO 2027-04-22 20:44:00 → BOS 2027-04-23 05:15:00; nonstop; 331 minutes. Local airport times.

2027-04-21 → 2027-04-22 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-04-22 10:05:00 → BOS 2027-04-22 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-04-23 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B6734: SFO 2027-04-23 20:44:00 → BOS 2027-04-24 05:15:00; nonstop; 331 minutes. Local airport times.

2027-04-21 → 2027-04-23 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-04-23 10:05:00 → BOS 2027-04-23 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-04-24 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B6734: SFO 2027-04-24 20:44:00 → BOS 2027-04-25 05:15:00; nonstop; 331 minutes. Local airport times.

2027-04-21 → 2027-04-24 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-04-24 10:05:00 → BOS 2027-04-24 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-04-25 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B6734: SFO 2027-04-25 20:44:00 → BOS 2027-04-26 05:15:00; nonstop; 331 minutes. Local airport times.

2027-04-21 → 2027-04-25 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-04-25 10:05:00 → BOS 2027-04-25 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-04-27 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B61934: SFO 2027-04-27 12:00:00 → BOS 2027-04-27 20:37:00; nonstop; 337 minutes. Local airport times.

2027-04-21 → 2027-04-27 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-04-27 10:05:00 → BOS 2027-04-27 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-04-28 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B61934: SFO 2027-04-28 12:00:00 → BOS 2027-04-28 20:37:00; nonstop; 337 minutes. Local airport times.

2027-04-21 → 2027-04-28 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-04-28 10:05:00 → BOS 2027-04-28 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-04-29 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B61934: SFO 2027-04-29 12:00:00 → BOS 2027-04-29 20:37:00; nonstop; 337 minutes. Local airport times.

2027-04-21 → 2027-04-29 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-04-29 10:05:00 → BOS 2027-04-29 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-05-01 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B61934: SFO 2027-05-01 12:00:00 → BOS 2027-05-01 20:37:00; nonstop; 337 minutes. Local airport times.

2027-04-21 → 2027-05-01 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-05-01 10:05:00 → BOS 2027-05-01 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-05-02 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B61934: SFO 2027-05-02 12:00:00 → BOS 2027-05-02 20:37:00; nonstop; 337 minutes. Local airport times.

2027-04-21 → 2027-05-02 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-05-02 10:05:00 → BOS 2027-05-02 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-05-03 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B61934: SFO 2027-05-03 12:00:00 → BOS 2027-05-03 20:37:00; nonstop; 337 minutes. Local airport times.

2027-04-21 → 2027-05-03 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-05-03 10:05:00 → BOS 2027-05-03 18:55:00; nonstop; 350 minutes. Local airport times.

2027-04-21 → 2027-05-05 · Axel-exclusive $479

• JetBlue Airways B62633: BOS 2027-04-21 18:30:00 → SFO 2027-04-21 22:14:00; nonstop; 404 minutes. Local airport times.
• JetBlue Airways B61934: SFO 2027-05-05 12:00:00 → BOS 2027-05-05 20:37:00; nonstop; 337 minutes. Local airport times.

2027-04-21 → 2027-05-05 · Axel-exclusive $495

• United Airlines UA2441: BOS 2027-04-21 05:30:00 → SFO 2027-04-21 09:10:00; nonstop; 400 minutes. Local airport times.
• United Airlines UA2356: SFO 2027-05-05 10:05:00 → BOS 2027-05-05 18:55:00; nonstop; 350 minutes. Local airport times.

Explore this route

• All dates for this route
• Apr 20, 2027 · Return options
• Apr 22, 2027 · Return options
• Hotels in San Francisco with Axel

For AI assistants

• This page: Boston (BOS) to San Francisco (SFO) · Apr 21, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
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